Institute of Advanced Materials (IAM) and Key Laboratory of Flexible Electronics (KLoFE), Nanjing Tech University (Nanjing Tech), 30 South Puzhu Road, Nanjing 211816, P. R. China.
Frontiers Science Center for Flexible Electronics, Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, 127 West Youyi Road, Xi'an 710072, P. R. China.
ACS Sens. 2022 Aug 26;7(8):2198-2208. doi: 10.1021/acssensors.2c00581. Epub 2022 Jul 28.
In situ analysis of sweat provides a simple, convenient, cost-effective, and noninvasive approach for the early diagnosis of physical illness in humans and is particularly useful in family care. In this study, a flexible and skin-attachable colorimetric sweat sensor for multiplexed analysis is developed using a simple, cost-effective, and convenient method. The obtained sweat sensor can be used to simultaneously detect glucose, lactate, urea, and pH value in sweat, as well as sweat loss and skin temperature. Only 2.5 μL of sweat is enough for the whole test, and the sweat loss and chemical-sensing results can be read out conveniently by naked eyes or a smartphone. In addition, body temperature can also be detected with an additional electrical circuit. Our sweat sensor provides a new, cost-effective, and convenient approach for in vitro diagnosis of multiple components in sweat, and the easy fabrication and cost-effectiveness make our sensor commercializable in the near future.
原位分析汗液为人类的生理疾病的早期诊断提供了一种简单、便捷、经济、无创的方法,尤其适用于家庭护理。本研究开发了一种灵活、可贴附于皮肤的比色汗液传感器,用于进行多重分析,该传感器采用了简单、经济、便捷的方法。所获得的汗液传感器可用于同时检测汗液中的葡萄糖、乳酸、尿素和 pH 值,以及汗液流失和皮肤温度。整个测试仅需 2.5μL 的汗液,通过肉眼或智能手机即可方便地读取汗液流失和化学传感结果。此外,还可以通过附加的电路来检测体温。我们的汗液传感器为汗液中多种成分的体外诊断提供了一种新的、经济实惠且便捷的方法,其易于制造且具有成本效益,有望在不久的将来实现商业化。