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基于功能近红外光谱的无创经颅电刺激靶向神经调控:综述。

Non-invasive transcranial electrical brain stimulation guided by functional near-infrared spectroscopy for targeted neuromodulation: a review.

机构信息

School of Mechanical Engineering, Pusan National University, Busan 46241, Republic of Korea.

Department of Cogno-Mechatronics Engineering, Pusan National University, Busan 46241, Republic of Korea.

出版信息

J Neural Eng. 2022 Aug 17;19(4). doi: 10.1088/1741-2552/ac857d.

Abstract

One of the primary goals in cognitive neuroscience is to understand the neural mechanisms on which cognition is based. Researchers are trying to find how cognitive mechanisms are related to oscillations generated due to brain activity. The research focused on this topic has been considerably aided by developing non-invasive brain stimulation techniques. The dynamics of brain networks and the resultant behavior can be affected by non-invasive brain stimulation techniques, which make their use a focus of interest in many experiments and clinical fields. One essential non-invasive brain stimulation technique is transcranial electrical stimulation (tES), subdivided into transcranial direct and alternating current stimulation. tES has recently become more well-known because of the effective results achieved in treating chronic conditions. In addition, there has been exceptional progress in the interpretation and feasibility of tES techniques. Summarizing the beneficial effects of tES, this article provides an updated depiction of what has been accomplished to date, brief history, and the open questions that need to be addressed in the future. An essential issue in the field of tES is stimulation duration. This review briefly covers the stimulation durations that have been utilized in the field while monitoring the brain using functional-near infrared spectroscopy-based brain imaging.

摘要

认知神经科学的主要目标之一是理解认知所基于的神经机制。研究人员试图发现认知机制与由于大脑活动产生的振荡之间的关系。由于开发了非侵入性脑刺激技术,该主题的研究得到了极大的帮助。非侵入性脑刺激技术可以影响脑网络的动态及其产生的行为,这使得它们在许多实验和临床领域成为关注的焦点。一种基本的非侵入性脑刺激技术是经颅电刺激 (tES),可细分为经颅直流电刺激和经颅交流电刺激。由于在治疗慢性疾病方面取得了有效的效果,tES 最近变得更加知名。此外,在 tES 技术的解释和可行性方面也取得了非凡的进展。本文总结了 tES 的有益效果,提供了迄今为止所取得成就的最新描述、简要历史以及未来需要解决的开放性问题。tES 领域的一个重要问题是刺激持续时间。本文简要介绍了在使用基于功能近红外光谱的脑成像监测大脑时,该领域中使用的刺激持续时间。

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