Thakur Nagendra, Singh Satya P, Zhang Changyi
Department of Microbiology, Sikkim University, 6th Mile, Tadong 737102, Gangtok, Sikkim, India.
UGC-CAS Department of Biosciences, Saurashtra University, Rajkot 360005, Gujarat, India.
Curr Res Microb Sci. 2022 May 28;3:100141. doi: 10.1016/j.crmicr.2022.100141. eCollection 2022.
Extremophiles are group of microorganisms that possess ability to tolerate and live under the extremes of physico-chemical, geological and nutritional conditions. Such microorganisms are evolutionary relics and have evolved adaptation strategies at cellular, biochemical and molecular levels. They produce enzymes that are capable to maintain stability and function under the multitudes of extremities. These organisms also produce variety of other molecules and metabolites, such as extremolytes and surface-active compounds to protect against extremes of salinity, pH, pressure, temperatures and solar radiation. Investigations on these microorganisms can further open new avenues and opportunity for research and biotechnological applications in the areas of waste water treatment, bio-plastics, biofuel, cosmetics, agriculture, food and pharmaceuticals. Further, extremophiles have potential roles to play in bioremediation, astrobiology and biorefinery.
极端微生物是一类能够在极端的物理化学、地质和营养条件下耐受并生存的微生物。这类微生物是进化的遗迹,并且在细胞、生化和分子水平上进化出了适应策略。它们产生的酶能够在多种极端条件下保持稳定性和功能。这些生物还产生各种其他分子和代谢产物,如极端溶质和表面活性化合物,以抵御盐度、pH值、压力、温度和太阳辐射等极端条件。对这些微生物的研究可以进一步为废水处理、生物塑料、生物燃料、化妆品、农业、食品和制药等领域的研究和生物技术应用开辟新的途径和机会。此外,极端微生物在生物修复、天体生物学和生物精炼中具有潜在作用。