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[肺错构瘤。发育异常性病变还是真性肿瘤?100例个人病例研究]

[Hamartoma of the lung. Dysontogenetic lesion or true tumor? Study of 100 personal cases].

作者信息

Hackl H

出版信息

Zentralbl Allg Pathol. 1987;133(1):7-28.

PMID:3591037
Abstract

100 hamartomas of the lung (89 operative and 11 autopsy specimens were examined in detail and all parameters statistically correlated. Clinical identification and diagnosis have improved continuously in the last two decades. Men are affected more frequently. The hamartomas of the middle lobes were exceptional from several points of view (size, growth form, age). The typical hamartoma does not become malignant. Those patients who have a co-existent bronchial carcinoma are generally younger than those who have malignant disease only. Precise investigation of various individual criteria demonstrated that the replacement of the old dysontogenesis theory through the concept of pure tumorigenesis (mesenchymoma) is not justified.

摘要

对100例肺错构瘤(89例手术标本和11例尸检标本进行了详细检查,并对所有参数进行了统计学关联分析。在过去二十年中,临床识别和诊断一直在不断改善。男性受影响更为频繁。中叶错构瘤在几个方面(大小、生长形式、年龄)都很特殊。典型的错构瘤不会恶变。患有并存支气管癌的患者通常比仅患有恶性疾病的患者年轻。对各种个体标准的精确研究表明,用纯肿瘤发生(间叶瘤)概念取代旧的发育异常理论是不合理的。

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