Yu Dejun, Liu Zuyao, Wang Hongqing, Yao Ran, Li Fu, Yang Yang, Sun Fenglong
Second Department of Orthopedics, Beijing Rehabilitation Hospital, Capital University of Medical Sciences, Beijing, China.
Department of Orthopaedics, Beijing Rehabilitation Hospital, Capital University of Medical Sciences, Beijing, China.
Front Surg. 2022 Jul 13;9:942195. doi: 10.3389/fsurg.2022.942195. eCollection 2022.
The present study was designed for the contrastive analysis of conservative and percutaneous kyphoplasty (PKP) on pain severity and recovery of injured vertebrae in elderly patients with acute symptomatic osteoporotic vertebral compression fracture (OVCF).
A total of 60 elderly patients with acute symptomatic OVCF were divided into two groups according to different treatment protocols, with 30 patients in each group. Patients in the Con group received conservative treatment, while patients in the PKP group received percutaneous kyphoplasty treatment. Clinical evaluation included the visual analogue scale (VAS), the Dallas pain questionnaire, the vertebral body leading edge height, the Cobb angle of injured vertebrae, the MOS item short-form health survey (SF-36), the Barthel index, and the mini-mental state examination (MMSE).
At 3 days, 3 months, and 6 months post-treatment, the score of VAS and the Cobb angle of injured vertebrae in patients of the PKP group were all significantly lower than those in the Con group (< 0.05), while the height of vertebral body leading edge in patients of the PKP group was significantly longer than that in the Con group (< 0.05). At 6 months post-treatment, the scores of the four dimensions of the Dallas pain questionnaire scale in the PKP group were all significantly lower than those in the Con group (< 0.05), while the score of SF-36 (PCS), SF-36 (MCS), and Barthel index in patients of the PKP group were all significantly lower than those in the Con group (< 0.05), and there was no significant difference in the scores of MMSE between these two groups (> 0.05).
Compared with conservative treatment, PKP treatment of elderly patients with acute symptomatic OVCF provides rapid pain relief, restoration of damaged vertebral body height, correction of Cobb's angle, and improved quality of life.
本研究旨在对比分析保守治疗与经皮椎体后凸成形术（PKP）对老年急性症状性骨质疏松性椎体压缩骨折（OVCF）患者疼痛严重程度及伤椎恢复情况的影响。
将60例老年急性症状性OVCF患者按不同治疗方案分为两组，每组30例。Con组患者接受保守治疗，PKP组患者接受经皮椎体后凸成形术治疗。临床评估包括视觉模拟评分法（VAS）、达拉斯疼痛问卷、椎体前缘高度、伤椎Cobb角、简明健康状况调查量表（SF-36）、Barthel指数及简易精神状态检查表（MMSE）。
治疗后3天、3个月及6个月时，PKP组患者的VAS评分及伤椎Cobb角均显著低于Con组（<0.05），而PKP组患者的椎体前缘高度显著长于Con组（<0.05）。治疗后6个月时，PKP组达拉斯疼痛问卷量表四个维度的得分均显著低于Con组（<0.05），而PKP组患者的SF-36（生理健康总分）、SF-36（心理健康总分）及Barthel指数均显著低于Con组（<0.05），两组MMSE得分差异无统计学意义（>0.05）。
与保守治疗相比，PKP治疗老年急性症状性OVCF患者可快速缓解疼痛，恢复受损椎体高度，矫正Cobb角，并改善生活质量。
