Wei Huawei, Zhang Qiuxue, Song Bing, Yue Hongwei, Li Jing, Zhang Hongjian, Wang Yanming
Department of Orthopedics, Qilu Hospital Dezhou Hospital, Shandong University, Dezhou, Shandong, China.
Minimally Invasive Surgery Centre, Qilu Hospital Dezhou Hospital, Shandong University, Dezhou, Shandong, China.
Front Surg. 2025 May 14;12:1539057. doi: 10.3389/fsurg.2025.1539057. eCollection 2025.
Osteoporotic vertebral compression fractures (OVCFs) are common in older populations, and cause pain and kyphosis, impacting patient quality of life. This study aimed to determine the optimal timing of percutaneous vertebroplasty (PVP) for the treatment of OVCFs.
This retrospective cohort study included 120 older patients with OVCFs admitted to our hospital between January 2020 and December 2022. Patients were divided into three groups according to the timing of PVP surgery: Group A, within 7 days of the OVCF; Group B, 8-14 days after the OVCF; and Group C, 15-28 days after the OVCF. Preoperative and postoperative visual analog scale scores, the Oswestry Disability Index, vertebral height, Cobb angle, and complications were compared among the three groups.
PVP surgery within 7 days of the OVCF led to rapid pain relief and restoration of vertebral function; preoperative visual analog scale scores and the Oswestry Disability Index were significantly higher in this group compared with the other two groups, but no significant differences among the three groups were observed postoperatively. However, early surgery was also associated with a higher rate of bone cement leakage compared with the other two groups, whereas delayed PVP was associated with a greater incidence of deep vein thrombosis and urinary infections.
The timing of PVP surgery in the management of OVCFs impacts patient outcomes. Early surgical treatment may result in greater pain relief, improved vertebral function, and fewer complications, but patient-specific factors should be considered when determining the optimal surgical timing.
骨质疏松性椎体压缩骨折（OVCFs）在老年人群中很常见，会引起疼痛和脊柱后凸，影响患者生活质量。本研究旨在确定经皮椎体成形术（PVP）治疗OVCFs的最佳时机。
这项回顾性队列研究纳入了2020年1月至2022年12月期间我院收治的120例老年OVCFs患者。根据PVP手术时机将患者分为三组：A组，在OVCF发生后7天内；B组，在OVCF发生后8 - 14天；C组，在OVCF发生后15 - 28天。比较三组患者术前和术后的视觉模拟评分、Oswestry功能障碍指数、椎体高度、Cobb角及并发症情况。
在OVCF发生后7天内进行PVP手术可迅速缓解疼痛并恢复椎体功能；与其他两组相比，该组术前视觉模拟评分和Oswestry功能障碍指数显著更高，但术后三组间未观察到显著差异。然而，与其他两组相比，早期手术骨水泥渗漏率也更高，而延迟PVP则与深静脉血栓形成和泌尿系统感染的发生率更高有关。
PVP手术治疗OVCFs的时机影响患者预后。早期手术治疗可能带来更大程度的疼痛缓解、改善椎体功能并减少并发症，但在确定最佳手术时机时应考虑患者的具体因素。
