Stanek G, Flamm H, Groh V, Hirschl A, Kristoferitsch W, Neumann R, Schmutzhard E, Wewalka G
Zentralbl Bakteriol Mikrobiol Hyg A. 1987 Feb;263(3):442-9. doi: 10.1016/s0176-6724(87)80106-2.
From April 1984 to July 1985 873 cases of Borrelia infections were registered at the Hygiene Institute of the University of Vienna. 2609 serum samples of these patients were investigated for antibodies against B. burgdorferi by means of IFA- and ELISA-tests. Erythema chronicum migrans (ECM) was recognized in 60.9% of patients, neurological abnormalities were recorded in 23.4% of which the majority manifested themselves as polyradiculitis and meningopolyneuritis (MPN). Acrodermatitis chronica atrophicans (ACA) was recognized in 11.5%. A small number of patients suffered from Lymphadenosis cutis benigna (LCB), arthritis and cardiac abnormalities. Sixty percent of patients were females and 40% males. Infections were found in all age groups ranging from 2-83 years in females and 1-85 years in males. Tick- or insect-bites prior to the onset of illness were reported by 47.2% and 15.6% of patients, respectively. The main vector is the hard tick Ixodes ricinus. Flying insects from the family tabanidae, i.e. Chrysops caecutiens and Haematopota species, must also be considered as transmitters. Antibodies to B. burgdorferi were found in 22.3%, 93.6% and 100% of sera from patients with ECM, MPN and ACA, respectively. Six of 11 patients with LCB and all with arthritis and cardiac abnormalities showed serologic reactivity. Geographically, Borrelia infections are distributed in all states of Austria. The seasonal distribution of cases show a peak in July and August, but the onset of clinical manifestation could be observed throughout the year. These results present Austria as an area where tick- or insect-borne Borrelia infections are very frequent and endemic in all Austrian states.
1984年4月至1985年7月，维也纳大学卫生研究所登记了873例疏螺旋体感染病例。对这些患者的2609份血清样本进行了间接免疫荧光法（IFA）和酶联免疫吸附测定（ELISA）检测，以检测抗伯氏疏螺旋体的抗体。60.9%的患者被诊断为慢性游走性红斑（ECM），23.4%的患者有神经功能异常，其中大多数表现为多发性神经根炎和脑膜多发性神经炎（MPN）。11.5%的患者被诊断为萎缩性慢性肢端皮炎（ACA）。少数患者患有良性皮肤淋巴细胞增生症（LCB）、关节炎和心脏异常。60%的患者为女性，40%为男性。各年龄组均发现有感染病例，女性年龄范围为2至83岁，男性为1至85岁。分别有47.2%和15.6%的患者报告在发病前有蜱虫或昆虫叮咬史。主要传播媒介是蓖麻硬蜱。虻科的飞行昆虫，即盲虻和斑虻属物种，也必须被视为传播者。分别在60.9%、93.6%和100%的ECM、MPN和ACA患者血清中发现了抗伯氏疏螺旋体抗体。11例LCB患者中有6例以及所有患有关节炎和心脏异常的患者均表现出血清学反应。从地理分布来看，疏螺旋体感染在奥地利所有州均有发生。病例的季节性分布在7月和8月出现高峰，但全年均可观察到临床表现的发作。这些结果表明，奥地利是一个蜱虫或昆虫传播的疏螺旋体感染非常频繁且在奥地利所有州均为地方性感染的地区。
