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人格特质会影响轻躁狂检查表-32在双相情感障碍筛查中的有效性。

Personality traits influence the effectiveness of hypomania checklist-32 in screening for bipolar disorder.

作者信息

Wang Qiang, Sui Aiping, Gong Lin, Chattun Mohammad Ridwan, Han Ruichen, Cao Qiuyun, Shen Diwen, Zhang Yuzhe, Zhao Peng

机构信息

Department of Medical Psychology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China.

Jinling Institute of Technology, Nanjing, China.

出版信息

Front Psychiatry. 2022 Jul 15;13:919305. doi: 10.3389/fpsyt.2022.919305. eCollection 2022.

Abstract

BACKGROUND

It is clinically challenging to distinguish bipolar disorder (BD) from major depressive disorder (MDD) in the early stages. While the hypomania checklist-32 (HCL-32) is a proper auxiliary tool that is useful to differentiate between BD and MDD, there is currently no standard cut-off value. The variations in HCL-32 cut-off values could potentially be influenced by personality traits. Therefore, the aim of this study is to explore the effect of personality traits on the screening performance of HCL-32.

METHODS

In this retrospective cross-sectional study, 168 patients with BD or MDD were evaluated with the Eysenck Personality Questionnaire (EPQ) and HCL-32. The associations between demographic data, diagnosis and clinical rating scales were analyzed.

RESULTS

Diagnosis was not associated with extraversion but was related to neuroticism. HCL-32 scores in typical extraverted patients were higher in contrast to atypical extraverted patients. The best cut-off value for BD recognition of typical and atypical extraversion groups were 15 and 12.5, respectively. In patients with MDD, HCL-32 score of typical neuroticism was higher than the atypical type, but there was no difference in patients with BD. In typical neuroticism, there was no difference in HCL-32 scores between patients with MDD and BD. But among atypical neurotic patients, HCL-32 scores of BD were higher compared to MDD, with a cut-off value of 14.5.

LIMITATIONS

This study had a small sample size.

CONCLUSION

HCL-32 scores were affected by personality traits, with higher scores for typical extraversion and neuroticism. Clinicians should also consider the patients' personality traits when referring to HCL-32 scores, so as to increase the recognition rate of BD and eliminate false positives.

摘要

背景

在早期阶段,临床上很难将双相情感障碍(BD)与重度抑郁症(MDD)区分开来。虽然轻躁狂症状清单-32(HCL-32)是区分BD和MDD的有用辅助工具,但目前尚无标准的临界值。HCL-32临界值的变化可能会受到人格特质的影响。因此,本研究旨在探讨人格特质对HCL-32筛查性能的影响。

方法

在这项回顾性横断面研究中,对168例BD或MDD患者进行了艾森克人格问卷(EPQ)和HCL-32评估。分析了人口统计学数据、诊断与临床评定量表之间的关联。

结果

诊断与外向性无关,但与神经质有关。典型外向型患者的HCL-32得分高于非典型外向型患者。典型和非典型外向型组识别BD的最佳临界值分别为15和12.5。在MDD患者中,典型神经质患者的HCL-32得分高于非典型类型,但BD患者之间没有差异。在典型神经质患者中,MDD和BD患者的HCL-32得分没有差异。但在非典型神经质患者中,BD的HCL-32得分高于MDD,临界值为(14.5)。

局限性

本研究样本量较小。

结论

HCL-32得分受人格特质影响,典型外向性和神经质得分较高。临床医生在参考HCL-32得分时也应考虑患者的人格特质,以提高BD的识别率并消除假阳性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8e2/9337268/a2a249acbb8f/fpsyt-13-919305-g001.jpg

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