De Faria Beatriz, Haridi Merna, Hutcheson Alana, Mehendale Teja
Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, USA.
Medical School, St. Martinus University, Willemstad, CUW.
Cureus. 2022 Jun 23;14(6):e26254. doi: 10.7759/cureus.26254. eCollection 2022 Jun.
Human papillomavirus (HPV) is the most common sexually transmitted infection (STI) in the United States. It most commonly affects the genital areas, as well as the mouth and throat. Research has shown that HPV is a cause of cervical cancer and is a potential cofactor in the development of cervical intraepithelial neoplasia (CIN). However, there have been limited cases reported on understanding this coinfection and its mechanism through the lens of molecular biology. We present a case of a 22-year-old female with complaints of persistent lesions on the labia for more than 6 months that have increased in number. Histopathology was suggestive of HPV. This case report emphasizes the importance of HPV and chlamydia coinfection as leading causes for persistence of condyloma acuminatum and low-grade squamous intraepithelial lesion (LSIL), and the importance of screening and clinically managing vaginal HPV.
人乳头瘤病毒（HPV）是美国最常见的性传播感染（STI）。它最常影响生殖器区域，以及口腔和咽喉。研究表明，HPV是宫颈癌的一个病因，并且是宫颈上皮内瘤变（CIN）发生发展的一个潜在协同因素。然而，通过分子生物学视角来理解这种合并感染及其机制的报道病例有限。我们报告一例22岁女性病例，其主诉阴唇持续性皮损超过6个月且数量增多。组织病理学提示为HPV感染。本病例报告强调了HPV与衣原体合并感染作为尖锐湿疣和低级别鳞状上皮内病变（LSIL）持续存在的主要原因的重要性，以及筛查和临床处理阴道HPV感染的重要性。
