Infectious Disease Medical Center Hamburg; University Hospital Schleswig-Holstein, Campus Kiel; Practice of Jessen² + Colleagues, Dr. Heiko Jessen and Dr. Arne Jessen, Berlin; Department of Medicine I, Bonn University Hospital.
Dtsch Arztebl Int. 2022 Aug 22;119(33-34):551-557. doi: 10.3238/arztebl.m2022.0287.
Many cases of monkeypox have been reported across Europe from early May 2022 onward. Initial publications suggest that nearly all of the affected persons to date have been men who have sex with men (MSM).
To characterize the German cases, an anonymous questionnaire was sent via the mailing lists of the German AIDS Society (Deutsche AIDS-Gesellschaft, DAIG) and the German Association of Outpatient Physicians for Infectious Diseases and HIV Medicine (Deutsche Arbeitsgemeinschaft ambulant tätiger Ärztinnen und Ärzte für Infektionskrankheiten und HIV-Medizin e.V., DAGNAE).
301 PCR-verified cases had been registered as of 23 June 2022. All of the affected persons were MSM, including 141 (46.7%) with HIV infection and 135 (44.7%) with pre-exposure prophylaxis (PrEP). The great majority of skin lesions were in the anal and genital areas. The most common general symptoms were fever, headache, limb pain, and, often, painfully swollen lymph nodes. Most infections to date have taken a relatively mild course: 5.0% of the patients were hospitalized, and none died. A high frequency of sexually transmitted infections (STI) was noted: only 41.0% of the patients had not been given a diagnosis of an STI in the six months before their monkeypox infection.
Monkeypox seems to be establishing itself as a new type of STI among MSM. In view of the rising case numbers, there is a need for a rapid information and vaccination campaign in the population at risk. Heightened alertness among phy - sicians is needed as well.
自 2022 年 5 月初以来，欧洲报告了多例猴痘病例。最初的出版物表明，迄今为止，几乎所有受影响的人都是男男性行为者（MSM）。
为了描述德国的病例特征，通过德国艾滋病协会（Deutsche AIDS-Gesellschaft，DAIG）和德国门诊传染病和 HIV 医学医师协会（Deutsche Arbeitsgemeinschaft ambulant tätiger Ärztinnen und Ärzte für Infektionskrankheiten und HIV-Medizin e.V.，DAGNAE）的邮件列表匿名发送了一份调查问卷。
截至 2022 年 6 月 23 日，已登记了 301 例经 PCR 证实的病例。所有受影响的人都是 MSM，包括 141 例（46.7%）HIV 感染和 135 例（44.7%）接受了暴露前预防（PrEP）。绝大多数皮肤损伤发生在肛门和生殖器区域。最常见的全身症状是发热、头痛、肢体疼痛，并且经常出现疼痛性肿胀的淋巴结。迄今为止，大多数感染的病程相对较轻：5.0%的患者住院，无人死亡。性传播感染（STI）的发生率很高：在感染猴痘之前的六个月内，只有 41.0%的患者没有被诊断出患有 STI。
猴痘似乎正在 MSM 中成为一种新的性传播感染。鉴于病例数量不断增加，需要在高危人群中迅速开展信息和疫苗接种运动。医生也需要提高警惕。
