Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Department of Emergency Medicine, Yale School of Medicine, New Haven, CT, USA.
Nicotine Tob Res. 2023 Feb 9;25(3):379-385. doi: 10.1093/ntr/ntac188.
E-cigarettes are increasingly being marketed as containing tobacco-free nicotine (TFN). There is no data examining use of TFN e-cigarettes by young adults and how use may differ from non-TFN e-cigarettes. The current study aims to characterize young adult TFN e-cigarette use and examine differences between those who report using TFN and non-TFN e-cigarettes.
U.S. young adults (18-25) with lifetime e-cigarette use (n = 927) were recruited via online panels in Fall 2021 and answered questions about TFN and non-TFN e-cigarettes. Participants were categorized by lifetime TFN e-cigarette use status (yes vs. no; 34% yes). Bivariate comparisons examined differences in e-cigarette characteristics (device type, flavors, nicotine concentration) between the TFN and non-TFN groups. Binary logistic regression models examined associations between lifetime frequency of vaping (<100 vs. ≥100 times), and other tobacco product, cannabis, and/or alcohol use and lifetime TFN e-cigarette use (yes vs. no). Adjusted models include age, race/ethnicity, vaping onset age, and sex.
In multivariable adjusted models, lifetime TFN e-cigarette use was associated with younger age, greater lifetime vaping, and nicotine pouch use. Young adults who used TFN e-cigarettes were more likely to report fruit, mint, menthol, and beverage flavors and know their e-liquid nicotine concentration compared with those who used non-TFN e-cigarettes.
Among young adults who have used e-cigarettes, more frequent e-cigarette use and use of nicotine pouches, which can also contain TFN, were associated with TFN e-cigarette use. Understanding behaviors and characteristics of those using TFN e-cigarettes is critical to regulation of TFN containing products.
This study characterizes young adults who report experience with tobacco free nicotine (TFN) e-cigarettes and compares them to those who have not used TFN e-cigarettes. Young adults with more frequent e-cigarette use and use of nicotine pouches are more likely to report TFN e-cigarette use.
电子烟越来越多地被宣传为含有无烟草尼古丁（TFN）。目前尚无数据研究年轻人使用 TFN 电子烟的情况，以及这种使用方式与非 TFN 电子烟的使用方式有何不同。本研究旨在描述年轻成年人使用 TFN 电子烟的情况，并研究报告使用 TFN 和非 TFN 电子烟的人群之间的差异。
2021 年秋季，通过在线小组招募了美国 18-25 岁有终身电子烟使用史的年轻人（n = 927），并询问了他们关于 TFN 和非 TFN 电子烟的问题。参与者根据终身 TFN 电子烟使用情况进行分类（是/否；34%是）。采用双变量比较，研究 TFN 和非 TFN 组之间电子烟特征（设备类型、口味、尼古丁浓度）的差异。采用二项逻辑回归模型，研究一生中电子烟使用频率（<100 次/≥100 次）、其他烟草制品、大麻和/或酒精使用与终身 TFN 电子烟使用（是/否）之间的关联。调整模型包括年龄、种族/民族、电子烟使用起始年龄和性别。
在多变量调整模型中，终身 TFN 电子烟使用与年龄较小、更大的终生电子烟使用量和尼古丁袋使用有关。与使用非 TFN 电子烟的年轻人相比，使用 TFN 电子烟的年轻人更有可能报告水果、薄荷、薄荷醇和饮料口味，并且知道他们的电子烟液尼古丁浓度。
在使用过电子烟的年轻人中，更频繁的电子烟使用和尼古丁袋的使用（也可能含有 TFN）与 TFN 电子烟的使用有关。了解使用 TFN 电子烟的人群的行为和特征对于 TFN 含产品的监管至关重要。
本研究描述了报告有 TFN 电子烟使用经验的年轻成年人，并将他们与未使用 TFN 电子烟的人进行了比较。更频繁地使用电子烟和使用尼古丁袋的年轻人更有可能报告 TFN 电子烟的使用。
