Schölmerich J, Freudemann A, Köttgen E, Wietholtz H, Steiert B, Löhle E, Häussinger D, Gerok W
Am J Clin Nutr. 1987 Jun;45(6):1480-6. doi: 10.1093/ajcn/45.6.1480.
Zinc supplementation is beneficial in some clinical conditions. Histidine has been shown to improve zinc absorption in animals. To test its influence on zinc absorption in humans, we studied the bioavailability of zinc from zinc-histidine complexes as compared to zinc sulfate in 10 healthy volunteers. Ingestion of zinc complexed with histidine at a ratio of 1:2 or 1:12 increased serum-zinc concentration 25% more than ingestion of zinc sulfate. Calculated uptake was 30-40% increased with zinc histidine over zinc sulfate. Urinary excretion was not different with any preparation. Application of 15 mg zinc as zinc histidine 1:2 gave an identical serum-zinc response as 45 mg zinc taken as zinc sulfate. Zinc histidine complexes are better absorbed than zinc sulfate in humans.
补充锌在某些临床情况下是有益的。已证明组氨酸可改善动物对锌的吸收。为了测试其对人体锌吸收的影响，我们在10名健康志愿者中研究了与硫酸锌相比，锌 - 组氨酸复合物中锌的生物利用度。摄入组氨酸与锌比例为1:2或1:12的锌复合物，血清锌浓度比摄入硫酸锌时高出25%。与硫酸锌相比，锌组氨酸的计算吸收量增加了30 - 40%。任何制剂的尿排泄都没有差异。以组氨酸与锌比例为1:2的形式应用15毫克锌，其血清锌反应与摄入45毫克硫酸锌相同。在人体中，锌组氨酸复合物比硫酸锌吸收更好。
