Relationship of dose to local control in advanced stage III and IV head and neck cancer treated by surgery and postoperative radiotherapy.

Retrospective analysis of 76 patients with locally advanced squamous cell carcinoma of multiple head and neck sites, who were treated by surgical resection and either 4,000-5,000, 6,000, or 6,600 rad postoperative external beam radiotherapy, revealed reduced local recurrence rates with increasing postoperative radiation dose.