Kawamoto M M, Garabrant D H, Held J, Balmes J R, Patzman J, Dimick D V, Simonowitz J A, Bernstein L
Am J Ind Med. 1987;11(5):505-15. doi: 10.1002/ajim.4700110504.
We measured exposures to total dust, vertically elutriated dust, and endotoxin and studied acute pulmonary responses among 128 workers in the cotton garnetting and mattress assembly industries. Previous studies in this segment of industry have not characterized endotoxin exposures or related them to pulmonary responses. The median 8-hour time-weighted average total dust was 0.72 mg/m3, the median vertically elutriated dust was 0.22 mg/m3, and the median endotoxin concentration was 5.2 ng/m3. Ten percent of the subjects reported chest tightness or dyspnea on Mondays. Thirteen percent of the subjects reported symptoms of chronic bronchitis. Although there was no relationship between changes in pulmonary function across the workshift and either total dust, vertically elutriated dust, or endotoxin exposure, 13% of the subjects had greater than 5% decrements in FEV1 over the workshift.
我们测量了128名棉籽加工和床垫组装行业工人接触总粉尘、垂直淘析粉尘和内毒素的情况,并研究了他们的急性肺部反应。此前在该行业领域的研究尚未对接触内毒素的情况进行描述,也未将其与肺部反应联系起来。8小时时间加权平均总粉尘中位数为0.72毫克/立方米,垂直淘析粉尘中位数为0.22毫克/立方米,内毒素浓度中位数为5.2纳克/立方米。10%的受试者报告周一出现胸闷或呼吸困难。13%的受试者报告有慢性支气管炎症状。尽管整个工作日班期间肺功能变化与总粉尘、垂直淘析粉尘或内毒素接触之间没有关系,但13%的受试者在工作日班期间第一秒用力呼气容积(FEV1)下降超过5%。