Rylander R, Haglind P
Environ Health Perspect. 1986 Apr;66:83-6. doi: 10.1289/ehp.866683.
Workers from cotton mills were exposed to cotton dust during carding in an experimental cardroom. Cotton from different geographical locations with varying amounts of endotoxin were used. Exposure levels ranged from 0.6 to 3.6 mg dust/m3 (from a vertical elutriator) and from 0.1 to 8.0 micrograms/m3 of endotoxin. No relationship was found between the decrease in FEV1 over the workshift and the amount of airborne dust. Airborne endotoxin correlated with the decrease in FEV1 and the increase in blood neutrophils. The FEV1 decrease was more pronounced among smokers. The data suggest that the amount of airborne endotoxin determines the risk for development of the acute symptoms in the byssinosis syndrome.
在一个实验性梳棉车间中,棉纺厂工人在梳棉过程中接触到了棉花粉尘。使用了来自不同地理位置、内毒素含量各异的棉花。暴露水平范围为0.6至3.6毫克粉尘/立方米(来自垂直淘析器)以及0.1至8.0微克/立方米的内毒素。未发现整个工作班次中第一秒用力呼气量(FEV1)的下降与空气中粉尘量之间存在关联。空气中的内毒素与FEV1的下降以及血液中性粒细胞的增加相关。在吸烟者中,FEV1的下降更为明显。数据表明,空气中内毒素的量决定了棉尘肺综合征急性症状发生的风险。