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COVID-19 相关的双侧急性虹膜色素脱失伴眼压升高。

COVID-19-related bilateral acute de-pigmentation of iris with ocular hypertension.

机构信息

Department of Ophthalmology, Cornea Anterior Segment Services, Eye-Q Super Speciality Eye Hospitals, Gurugram, Haryana, India.

出版信息

Indian J Ophthalmol. 2022 Aug;70(8):3136-3139. doi: 10.4103/ijo.IJO_75_22.

DOI:10.4103/ijo.IJO_75_22
PMID:35918989
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9672727/
Abstract

A 43-year-old male patient presented with acute blurring of vision in both eyes associated with photophobia, redness, and mild pain following coronavirus disease 2019 (Covid-19) infection. Clinical examination revealed extensive pigment dusting in the corneal endothelium and the trabecular meshwork with de-pigmentation bands in the iris periphery. The patient was managed empirically with topical anti-glaucoma medications for high intra-ocular pressure. The patient was prescribed systemic antibiotics including cephalosporins and amoxicillin for respiratory symptoms. A rare condition called bilateral acute de-pigmentation of iris (BADI) was suspected after ruling out common entities, for example, viral kerato-uveitis, pigment dispersion syndrome, and Fuchs iridocyclitis. Covid-19 infection and systemic antibiotics including cephalosporins have shown to cause BADI in the literature. The patient responded well with good outcome.

摘要

一位 43 岁男性患者因感染 2019 冠状病毒病(COVID-19)后出现双眼急性视力模糊,伴有畏光、眼红和轻度疼痛。临床检查显示角膜内皮和小梁网广泛色素尘,虹膜周边有脱色素带。患者因高眼压接受了经验性的局部抗青光眼药物治疗。患者因呼吸道症状服用了包括头孢菌素和阿莫西林在内的全身抗生素。在排除常见疾病(例如病毒性角结膜炎、色素播散综合征和 Fuchs 虹膜睫状体炎)后,怀疑该患者患有一种罕见疾病,即双侧急性虹膜脱色素(BADI)。COVID-19 感染和包括头孢菌素在内的全身抗生素已在文献中显示可引起 BADI。该患者反应良好,预后良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ba6/9672727/a2da6484518c/IJO-70-3136-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ba6/9672727/b171aee5891c/IJO-70-3136-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ba6/9672727/a2da6484518c/IJO-70-3136-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ba6/9672727/b171aee5891c/IJO-70-3136-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ba6/9672727/a2da6484518c/IJO-70-3136-g004.jpg

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Ocul Immunol Inflamm. 2021 May 19;29(4):719-721. doi: 10.1080/09273948.2021.1933073. Epub 2021 Jun 14.
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Bilateral acute iris transillumination (BAIT) syndrome: literature review.双侧急性虹膜透照(BAIT)综合征:文献综述
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严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染继发的眼部神经炎症反应——综述
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Medicine (Baltimore). 2024 Dec 6;103(49):e40782. doi: 10.1097/MD.0000000000040782.
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