巴西托坎廷斯州暴发疫情期间，出现了马亚罗病毒和基孔肯雅热病毒的再流行和合并感染。
Re-emergence of mayaro virus and coinfection with chikungunya during an outbreak in the state of Tocantins/Brazil.
机构信息
Retrovirology Laboratory, Federal University of São Paulo, São Paulo City, São Paulo, 04039-032, Brazil.
Central Public Health Laboratory of Tocantins (LACEN/TO), Palmas City, Tocantins, 77016-330, Brazil.
出版信息
BMC Res Notes. 2022 Aug 3;15(1):271. doi: 10.1186/s13104-022-06153-6.
OBJECTIVE
To perform a molecular screening to detect infections by the mayaro virus and possible coinfections with Chikungunya during an outbreak in the state of Tocantins/Brazil in 2017.
RESULTS
Of a total 102 samples analyzed in this study, 6 cases were identified with simultaneous infection between mayaro and chikungunya viruses (5.88%). In these 6 samples, the mean Cycle threshold (Ct) for CHIKV was 26.87 (SD ± 10.54) and for MAYV was 29.58 (SD ± 6.34). The mayaro sequences generated showed 95-100% identity to other Brazilian sequences of this virus and with other MAYV isolates obtained from human and arthropods in different regions of the world. The remaining samples were detected with CHIKV monoinfection (41 cases), DENV monoinfection (50 cases) and coinfection between CHIKV/DENV (5 cases). We did not detect MAYV monoinfections.
目的
在 2017 年巴西托坎廷斯州的一次疫情中，进行分子筛查以检测可能发生的马亚罗病毒感染和与基孔肯雅热的合并感染。
结果
在本研究分析的总共 102 个样本中，有 6 个样本同时感染马亚罗病毒和基孔肯雅热病毒（5.88%）。在这 6 个样本中，基孔肯雅热病毒的平均循环阈值（Ct）为 26.87（SD ± 10.54），马亚罗病毒为 29.58（SD ± 6.34）。生成的马亚罗病毒序列与该病毒的其他巴西序列以及从世界不同地区的人类和节肢动物中获得的其他马亚罗病毒分离株具有 95-100%的同一性。其余样本检测出基孔肯雅热病毒单一感染（41 例）、登革热病毒单一感染（50 例）以及基孔肯雅热病毒/登革热病毒合并感染（5 例）。我们未检测出马亚罗病毒单一感染。
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