Rede BIONORTE, Programa de Biodiversidade e Biotecnologia, Santarém, PA, Brasil.
Universidade Federal do Oeste do Pará, Campus Tapajós, Laboratório de Genética e Biodiversidade, Santarém, PA, Brasil.
Rev Soc Bras Med Trop. 2021 Mar 22;54:e0055-2020. doi: 10.1590/0037-8682-0055-2020. eCollection 2021.
Mayaro virus (MAYV) was found in Pará state, Brazil, in 1955. Since then, sporadic outbreaks have occurred in different regions of the country.
Serum sample were collected from 49 individuals in 2016 and were initially tested for dengue virus (DENV) by real-time (RT) polymerase chain reaction (PCR). DENV-negative samples were tested for MAYV and Oropouche virus (OROV) by multiplexed RT quantitative PCR.
All samples were negative for DENV and OROV, but MAYV was detected in four samples.
Differential diagnoses of acute febrile syndrome are required, especially in regions where several arboviruses with similar clinical manifestations are endemic.
1955 年,巴西帕拉州发现了马亚罗病毒(MAYV)。此后,该国不同地区陆续出现散发病例。
2016 年采集了 49 个人的血清样本,最初通过实时(RT)聚合酶链反应(PCR)检测登革热病毒(DENV)。对 DENV 阴性样本进行马亚罗病毒和奥罗普切病毒(OROV)多重 RT 定量 PCR 检测。
所有样本均为 DEN 和 OROV 阴性,但在 4 个样本中检测到马亚罗病毒。
需要进行急性发热综合征的鉴别诊断,特别是在存在多种具有类似临床表现的虫媒病毒的流行地区。