Vilaseca J, González A, Cid M C, Lopez-Vivancos J, Ortega A
Ann Rheum Dis. 1987 Apr;46(4):282-5. doi: 10.1136/ard.46.4.282.
To assess the diagnostic usefulness of temporal artery biopsy in temporal arteritis (TA) and establish clinical features capable of predicting its positivity we have retrospectively studied the biopsy specimens and the clinical features of 103 patients who had undergone temporal artery biopsy. Temporal artery biopsy reached a positive predictive value of 90.2% with respect to the final diagnosis based on the criteria proposed by Ellis and Ralston and the clinical course. The simultaneous presence of recent onset headache, jaw claudication, and abnormalities of the temporal arteries on physical examination had a specificity of 94.8% with respect to the histological diagnosis and of 100% with respect to final diagnosis. The presence of any of these clinical features, though of little specificity (34.4%), had a sensitivity of 100% with respect to histological diagnosis, selecting a group of patients in whom temporal artery biopsy has more discriminative value.
为评估颞动脉活检在颞动脉炎（TA）中的诊断效用，并确定能够预测其阳性结果的临床特征，我们回顾性研究了103例接受颞动脉活检患者的活检标本和临床特征。根据埃利斯和拉尔斯顿提出的标准及临床病程，颞动脉活检对于最终诊断的阳性预测值达90.2%。近期发作的头痛、颌跛行和体格检查时颞动脉异常同时出现，对于组织学诊断的特异性为94.8%，对于最终诊断的特异性为100%。这些临床特征中任何一项的存在，尽管特异性较低（34.4%），但对于组织学诊断的敏感性为100%，从而筛选出一组颞动脉活检具有更高鉴别价值的患者。
