红细胞沉降率在风湿性多肌痛/巨细胞动脉炎综合征诊断与管理中的应用
The ESR in the diagnosis and management of the polymyalgia rheumatica/giant cell arteritis syndrome.
作者信息
Ellis M E, Ralston S
出版信息
Ann Rheum Dis. 1983 Apr;42(2):168-70. doi: 10.1136/ard.42.2.168.
Abstract
A review of 80 patients with the polymyalgia rheumatica/giant cell arteritis (PMR/GCA) syndrome has revealed that the erythrocyte sedimentation rate (ESR) is normal in 22.5% of cases at presentation. Too much reliance on the ESR as a screening test led to delay in diagnosis in 10 patients. Serious complications occurred in 4 patients with a normal or minimally raised ESR. Analysis of follow-up data at 4 weeks showed no significant correlation between change in the ESR and change in symptoms, and at subsequent clinical attendances symptoms did not consistently parallel the ESR. Our results cast serious doubts on the use of the ESR as an entirely reliable diagnostic and therapeutic aid in the PMR/GCA syndrome.
摘要
对80例风湿性多肌痛/巨细胞动脉炎（PMR/GCA）综合征患者的回顾显示，22.5%的患者在就诊时红细胞沉降率（ESR）正常。过度依赖ESR作为筛查试验导致10例患者诊断延迟。4例ESR正常或轻度升高的患者出现了严重并发症。对4周随访数据的分析表明，ESR变化与症状变化之间无显著相关性，且在随后的临床就诊中，症状与ESR并不始终平行。我们的结果对将ESR用作PMR/GCA综合征完全可靠的诊断和治疗辅助手段提出了严重质疑。
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