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孕期某些草药的不合理使用:来自也门的药物流行病学证据。

Irrational Use of Selected Herbal Medicines During Pregnancy: A Pharmacoepidemiological Evidence From Yemen.

作者信息

Ahmed Mansoor, Hwang Jung Hye, Ali Mohammed Nasr, Al-Ahnoumy Shafekah, Han Dongwoon

机构信息

School of Public Health, Dow University of Health Sciences, Karachi, Pakistan.

Department of Preventive Medicine, Hanyang University College of Medicine, Seoul, South Korea.

出版信息

Front Pharmacol. 2022 Jul 19;13:926449. doi: 10.3389/fphar.2022.926449. eCollection 2022.

Abstract

Recent research indicates irrational use of herbal medicine (HM) during pregnancy that can be harmful to the mother and development of baby. However, no study has been conducted to explore the use of HM among pregnant women in a conflict region. This was a cross-sectional research conducted in July and August in the year 2017, at three hospitals in Sana'a, Yemen. Postpartum women were interviewed via the structured instrument to collect data on patterns of HM used during pregnancy. A total of three hundred postpartum women participated in the study, with 59.3% (178) of them using at least one modality of HM in the previous pregnancy. Cinnamon ( L), ginger ( Z), barley ( P), and garlic ( A) were the most commonly used HM. Statistical analysis showed that consumers of HM had a higher rate of caesarian section and complications during and after the delivery. Consumption of HM during pregnancy was high including contraindicated modalities such as cinnamon ( L) and barley ( P). The use of potentially harmful modalities and association with complications pose a threat to the well-being of mothers and newborns. Further studies in this area will be helpful to generate evidence for the rational use of HM during pregnancy.

摘要

近期研究表明,孕期不合理使用草药可能对母亲和胎儿发育有害。然而,尚未有研究探讨冲突地区孕妇使用草药的情况。这是一项于2017年7月和8月在也门萨那的三家医院进行的横断面研究。通过结构化工具对产后妇女进行访谈,以收集孕期使用草药模式的数据。共有300名产后妇女参与了该研究,其中59.3%(178名)在之前的孕期中至少使用过一种草药。肉桂(L)、生姜(Z)、大麦(P)和大蒜(A)是最常用的草药。统计分析表明,使用草药的产妇剖宫产率以及分娩期间和产后的并发症发生率更高。孕期草药使用量较高,包括肉桂(L)和大麦(P)等禁忌草药。使用潜在有害草药以及与并发症的关联对母亲和新生儿的健康构成威胁。该领域的进一步研究将有助于为孕期合理使用草药提供证据。

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