Liyu Xu, Department of Geriatrics, Zhejiang Hospital, Hangzhou, Zhejiang, People's Republic of China, Tel +86 13486183817, Fax +86 0571 87985201, Email
J Nutr Health Aging. 2022;26(8):806-813. doi: 10.1007/s12603-022-1831-7.
The study aimed to apply the frailty index (FI) to assess frailty status among Chinese centenarians and analyse its associated factors.
The study was a cross-sectional study.
The study included 1043 centenarians (742 females and 301 males) aged ≥100 years from the 2018 wave of the China Longitudinal Healthy Longevity Survey.
All participants were assessed for frailty by the FI. Basic characteristics, including age, height, weight, calf circumference, waist circumference, hip circumference, sex, years of education, financial status, exercise, fall status, coresidence, smoking, alcohol consumption, number of natural teeth, denture use, toothache, and tooth brushing, were collected. Multivariate logistic regression was used to analyse the associations between risk factors and frailty.
The average age of the participants was 102.06±2.55 years (range: 100-117 years). The FI ranged between 0.00 and 0.63. The mean FI for all participants was 0.27±0.13 (median 0.25; interquartile range 0.20-0.35). Participants were divided into quartiles. The number of natural teeth and denture use, coresidence, sex, exercise, and financial status showed significant associations with frailty classes (all P<0.05). Multivariate logistic regression analysis indicated that having ≤20 natural teeth without dentures (OR, 95% CI= 1.89(0.004-1.246), P<0.05), having ≤20 natural teeth with dentures (OR, 95% CI=2.21(0.158,1.432), P=0.015), living alone or in an institution (OR, 95% CI=1.68(0.182-0.849), P=0.002), lacking exercise (OR, 95% CI=2.54(0.616-1.246), P<0.001), having insufficient financial resources (OR, 95% CI=2.9(0.664-1.468), P<0.001), and being female (OR, 95% CI=1.47(0.137,0.634), P=0.002) were independent risk factors for frailty.
Chinese centenarian women are frailer than men. Having fewer natural teeth, living alone or in an institution, lacking exercise, and having insufficient financial resources were the factors associated with frailty among Chinese centenarians. Family conditions and healthy lifestyles may be important for frailty status in centenarians.
本研究旨在应用衰弱指数（FI）评估中国百岁老人的衰弱状况，并分析其相关因素。
本研究为横断面研究。
本研究纳入了来自 2018 年中国长寿纵向研究的 1043 名年龄≥100 岁的百岁老人（742 名女性和 301 名男性）。
所有参与者均采用 FI 评估衰弱状况。收集基本特征，包括年龄、身高、体重、小腿围、腰围、臀围、性别、受教育年限、经济状况、运动情况、跌倒情况、共同居住情况、吸烟、饮酒、天然牙数、义齿使用情况、牙痛和刷牙情况。采用多变量 logistic 回归分析危险因素与衰弱的关系。
参与者的平均年龄为 102.06±2.55 岁（范围：100-117 岁）。FI 范围为 0.00 至 0.63。所有参与者的平均 FI 为 0.27±0.13（中位数 0.25；四分位间距 0.20-0.35）。参与者被分为四组。天然牙数和义齿使用情况、共同居住情况、性别、运动情况和经济状况与衰弱程度显著相关（均 P<0.05）。多变量 logistic 回归分析表明，无义齿的天然牙数≤20 颗（OR，95%CI=1.89（0.004-1.246），P<0.05），有义齿的天然牙数≤20 颗（OR，95%CI=2.21（0.158，1.432），P=0.015），独居或住在机构（OR，95%CI=1.68（0.182-0.849），P=0.002），缺乏运动（OR，95%CI=2.54（0.616-1.246），P<0.001），经济资源不足（OR，95%CI=2.9（0.664-1.468），P<0.001），女性（OR，95%CI=1.47（0.137，0.634），P=0.002）是衰弱的独立危险因素。
中国百岁女性比男性更虚弱。天然牙数较少、独居或住在机构、缺乏运动以及经济资源不足是中国百岁老人衰弱的相关因素。家庭状况和健康的生活方式可能对百岁老人的衰弱状况很重要。
