Yang Zhijing, Liu Weiwei, Liu Huimin, Li Rong, Chang Lu, Kan Shaoning, Hao Ming, Wang Dongxu
Department of Oral and Maxillofacial Surgery, Hospital of Stomatology, Jilin University, Changchun, China.
Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling, Hospital of Stomatology, Jilin University, Changchun, China.
Front Bioeng Biotechnol. 2022 Jul 22;10:970041. doi: 10.3389/fbioe.2022.970041. eCollection 2022.
Polysaccharides are natural polymers widely present in animals, plants, and several microorganisms. Polysaccharides have remarkable properties, including easy extractions, degradability, and renewability, and have no apparent toxicity, making them ideal for biomedical applications. Moreover, polysaccharides are suitable for repairing oral tissue defects and treating oral diseases due to their excellent biocompatibility, biosafety, anti-inflammatory, and antibacterial properties. The oral cavity is a relatively complex environment vulnerable to numerous conditions, including soft tissue diseases, hard tissue disorders, and as well as soft and hard tissue diseases, all of which are complex to treat. In this article, we reviewed different structures of natural polysaccharides with high commercial values and their applications in treating various oral disease, such as drug delivery, tissue regeneration, material modification, and tissue repair.
多糖是广泛存在于动物、植物和多种微生物中的天然聚合物。多糖具有显著的特性，包括易于提取、可降解性和可再生性，且无明显毒性，使其成为生物医学应用的理想选择。此外，多糖因其优异的生物相容性、生物安全性、抗炎和抗菌特性，适用于修复口腔组织缺损和治疗口腔疾病。口腔是一个相对复杂的环境，易受多种病症影响，包括软组织疾病、硬组织疾病以及软硬组织疾病，所有这些病症的治疗都很复杂。在本文中，我们综述了具有高商业价值的天然多糖的不同结构及其在治疗各种口腔疾病中的应用，如药物递送、组织再生、材料改性和组织修复。
