el Fawal M A, Berg G A, Wheatley D J, Harland W A
Br Heart J. 1987 May;57(5):420-6. doi: 10.1136/hrt.57.5.420.
A detailed analysis of the extent of coronary artery atherosclerosis was made in 92 white subjects (66 men and 26 women) who died suddenly from ischaemic heart disease. Stenoses resulting in loss of greater than or equal to 75% of luminal cross sectional area (significant stenosis) were found in 90 subjects and these were more extensive in the proximal coronary tree than in the distal. Thirty nine per cent had triple vessel disease, 37% had double vessel disease, and 23% had single vessel disease. In addition one man had an isolated significant stenosis affecting the left main coronary artery. The frequency of significant stenoses in the left main coronary artery was greater in men than in women. The arteries that were least affected were the distal branches of the right coronary artery. A notable feature was the widespread nature of the coronary atherosclerosis: only 26 of the total of 1840 segments of coronary artery examined in the 92 victims could be described as having a normal intima (less than or equal to 10% loss of the area within the internal elastic lamina).
对92名因缺血性心脏病突然死亡的白人受试者（66名男性和26名女性）的冠状动脉粥样硬化程度进行了详细分析。在90名受试者中发现狭窄导致管腔横截面积损失大于或等于75%（显著狭窄），且这些狭窄在冠状动脉近端比远端更广泛。39%的人患有三支血管病变，37%的人患有双支血管病变，23%的人患有单支血管病变。此外，一名男性有孤立的显著狭窄，累及左主干冠状动脉。男性左主干冠状动脉显著狭窄的发生率高于女性。受影响最小的动脉是右冠状动脉的远端分支。一个显著特点是冠状动脉粥样硬化的广泛性：在92名受害者检查的总共1840段冠状动脉中，只有26段可描述为内膜正常（内弹性膜内面积损失小于或等于10%）。
