Bazarah Salem M, Alotaibi Ruba M, Alghamdi Rozan A, Waheeb Abdullah S, Rafeea Wareef A, Talab Sedrah K, Badawoud Hassan M
Department of Gastroenterology, King Abdulaziz University Hospital, Jeddah, SAU.
Department of Medicine, King Abdulaziz University Faculty of Medicine, Jeddah, SAU.
Cureus. 2022 Jul 4;14(7):e26542. doi: 10.7759/cureus.26542. eCollection 2022 Jul.
(. ) infection and gastroesophageal reflux disease (GERD) are widely spread clinical terms. GERD refers to the backflow of gastric acid to the esophagus and upper gastrointestinal tract, causing irritation. . is a gram-negative bacillus that adheres mainly to the gastric mucosa, causing peptic ulcers and gastritis. The nature of the relationship between GERD and . is yet to be explored, and few studies have been conducted. In contrast, some studies suggest a protective role of . against GERD. This study aimed to identify the demographic, clinical, and endoscopic findings of patients with GERD who underwent . testing.
A retrospective review of medical records at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, between 2015 and 2021 was conducted in June 2021. Our sample consisted of 255 individuals enrolled based on age and . status. In univariate analysis, we used frequency tests for qualitative data and measure of central tendency (MCT) for quantitative data. In bivariate analysis, we used the t-test and Pearson's chi-square test.
Of 255 GERD patients enrolled, 90 were positive and 165 were negative for . The majority were females (54 were positive and 93 were negative for ). Both groups mainly complained of abdominal pain. Endoscopically, gastritis was higher in the -positive group than in the -negative group.
In conclusion, the majority of GERD patients were . -negative, females, Saudis, and non-smokers.
（. ）感染和胃食管反流病（GERD）是广泛传播的临床术语。GERD是指胃酸反流至食管和上消化道，引起刺激。. 是一种革兰氏阴性杆菌，主要附着于胃黏膜，导致消化性溃疡和胃炎。GERD与. 之间关系的本质尚待探索，且相关研究较少。相比之下，一些研究表明. 对GERD有保护作用。本研究旨在确定接受. 检测的GERD患者的人口统计学、临床和内镜检查结果。
2021年6月对沙特阿拉伯吉达阿卜杜勒阿齐兹国王大学医院2015年至2021年期间的病历进行了回顾性研究。我们的样本包括255名根据年龄和. 状态入选的个体。在单变量分析中，我们对定性数据使用频率检验，对定量数据使用集中趋势度量（MCT）。在双变量分析中，我们使用t检验和Pearson卡方检验。
在纳入的255例GERD患者中，90例. 检测呈阳性，165例呈阴性。大多数为女性（. 检测阳性5�例，阴性93例）。两组主要主诉为腹痛。在内镜检查中，.阳性组胃炎的发生率高于.阴性组。
总之，大多数GERD患者. 检测呈阴性，为女性、沙特人且不吸烟。
