Pre-Clinical Research and Development, Kent Scientific Corporation, Torrington, Connecticut.
J Am Assoc Lab Anim Sci. 2022 Sep 1;61(5):406-411. doi: 10.30802/AALAS-JAALAS-22-000006. Epub 2022 Aug 10.
Noninvasive blood pressure measurement devices have gained popularity in recent years as an alternative to radiotelemetry and other invasive blood pressure measurement techniques. While many factors must be considered when choosing a measurement method, specific variables should be evaluated when using a tail-cuff blood pressure technique. Rodents have complex and dynamic thermal biology processes that involve fluctuating vasomotor tone of the tail. This and other factors that affect vascular tone, such as the autonomic response to stress, significantly affect peripheral blood flow. Awareness and consideration of thermoregulatory states and vasomotor tone can increase success and decrease variability when measuring blood pressure measurements using a tail-cuff measurement technique.
近年来，非侵入式血压测量设备作为无线电遥测和其他侵入式血压测量技术的替代方法越来越受欢迎。虽然在选择测量方法时需要考虑许多因素，但在使用尾部血压技术时应评估特定变量。啮齿动物具有复杂和动态的热生物学过程，涉及尾部血管舒缩张力的波动。这种情况以及其他影响血管张力的因素，如对压力的自主反应，会显著影响外周血流量。在使用尾部血压测量技术测量血压时，了解和考虑体温调节状态和血管舒缩张力可以提高成功率并减少变异性。
