Vardar Serenay, Özsoy Ünübol Tuğba, Ata Emre, Yılmaz Figen
Department of Physical Medicine and Rehabilitation, Health Sciences University, Sultan 2. Abdulhamid Han Training and Research Hospital, Istanbul, Turkey.
Turk J Phys Med Rehabil. 2022 Mar 1;68(1):149-153. doi: 10.5606/tftrd.2022.8172. eCollection 2022 Mar.
Since the beginning of the novel coronavirus disease-2019 (COVID-19) pandemic, physical medicine and rehabilitation specialists have played an important role in fighting this disease apart from the pulmonary rehabilitation. As a high number of patients have needed immobilization and intensive care unit (ICU) treatment, many complications have emerged inevitably. Heterotopic ossification (HO) is one of these complications. Herein, we present a case of young male patient who had widespread HO in his shoulders, elbows, and hips. Although he managed to survive, he still has difficulty in ambulation and daily living activities. Given the continuing high prevalence of COVID-19, many patients would need immobilization and ICU treatment. Therefore, causes of HO should be scrutinized, physicians and caregivers need to raise vigilance, and comprehensive protective measures should be put in place. On the other hand, as HO is used to be diagnosed quite frequently in the patients with neurological diseases, diagnosis of HO in the COVID-19 patients should not automatically be linked to the stay in the ICU. Yet, it is a fact that impaired immune response is prevalent both in COVID-19 and HO. The correlation between COVID-19 and HO is remarkable, but further research is needed to establish a causal relationship.
自2019年新型冠状病毒病（COVID-19）大流行开始以来，除了肺康复之外，物理医学与康复专家在抗击这种疾病中发挥了重要作用。由于大量患者需要制动和重症监护病房（ICU）治疗，许多并发症不可避免地出现了。异位骨化（HO）就是其中一种并发症。在此，我们报告一例年轻男性患者，其肩部、肘部和髋部广泛出现异位骨化。尽管他成功存活下来，但仍存在行走和日常生活活动困难。鉴于COVID-19的持续高流行率，许多患者将需要制动和ICU治疗。因此，应仔细研究异位骨化的病因，医生和护理人员需要提高警惕，并应采取全面的防护措施。另一方面，由于HO在神经疾病患者中过去经常被诊断出来，COVID-19患者中HO的诊断不应自动与在ICU的停留相关联。然而，事实上，免疫反应受损在COVID-19和HO中都很普遍。COVID-19与HO之间的相关性很显著，但需要进一步研究来建立因果关系。
