Institute of Stomatology, Rīga Stradiņš University, Riga, Latvia.
Oncology Centre of Latvia, Rīga East University Hospital, Riga, Latvia.
Perm J. 2022 Sep 14;26(3):139-144. doi: 10.7812/TPP/21.232. Epub 2022 Aug 11.
Melanoma is a global problem due to the rising numbers of skin melanoma cases. Current treatment guidelines for patients with stage IIA melanoma recommend only observation after surgery. In this report, the authors describe a patient with stage IIA skin melanoma treated with surgery and Rigvir virotherapy. Two years after the patient discovered a brown spot on the right cheek, surgery was indicated because the mass had started to ulcerate. Rigvir virotherapy was applied both before and after surgery. Observations made more than 7 years after surgery indicated no signs of disease progression. This case report illustrates an early treatment approach. Neoadjuvant treatment for early-stage melanoma is gaining more interest in both scientific and medical communities; therefore, the authors believe it is relevant to share their observations.
黑色素瘤是一个全球性问题，因为皮肤黑色素瘤病例的数量不断增加。目前对于 IIA 期黑色素瘤患者的治疗指南仅建议在手术后进行观察。在本报告中，作者描述了一位接受手术和 Rigvir 病毒疗法治疗的 IIA 期皮肤黑色素瘤患者。在患者发现右脸颊上有一个棕色斑点两年后，由于肿块开始溃疡，因此进行了手术。在手术前后都应用了 Rigvir 病毒疗法。手术后超过 7 年的观察表明没有疾病进展的迹象。本病例报告说明了一种早期治疗方法。新辅助治疗早期黑色素瘤在科学界和医学界都越来越受到关注；因此，作者认为分享他们的观察结果是相关的。
