Department of Urology, Celal Bayar University Faculty of Medicine, Manisa, Turkey.
Department of Urology, Manisa Merkez Efendi State Hospital, Manisa, Turkey.
J Ultrasound. 2023 Mar;26(1):99-105. doi: 10.1007/s40477-022-00705-z. Epub 2022 Aug 11.
Histopathological analysis of the relationship between penile elastography and erectile dysfunction.
12 patients who applied to our clinic for erectile dysfunction in the last 1 year and accepted this study were included. Preoperative two-dimensional shear wave elastography imaging was performed in 12 patients and recorded in the Pascal (kPa) unit. Approximately 0.5 × 0.5 × 0.5 cm tissue samples were taken from the right and left cavernous tissue during penile prosthesis implantation operation. Tissue samples were sent to the pathology department. The percentage of the area covered by muscle fibers and elastic fibers in the corpus cavernosum was noted semi-quantitatively (ratio of muscle fibers and cavernous body elastic fiber score). All data obtained were compared with each other.
Cavernous body elastic fiber score data(Grouped Score 1, 2 and 3) and percentage of cavernous body muscle fibers data (Grouped %10, %20, %30… %100) were compared with Shear wave elastography data (kPa). The results were not statistically significant according to the Kruskal Wallis Test. Cavernous body elastic fiber score and the percentage of cavernous body muscle fibers were also compared, it was not statistically significant according to the Kruskal Wallis test and Spearman's correlation test.
Penile shear wave elastography can be used clinically to quantitatively assess the amount of smooth muscle cells and elastic fibers in the penis, but it deserves to be studied with a larger number of patients and a more specific interpretation of the pathology preparation.
分析阴茎弹性成像与勃起功能障碍的关系的组织病理学。
将过去 1 年内因勃起功能障碍而到我院就诊并同意参加本研究的 12 例患者纳入本研究。对 12 例患者进行术前二维剪切波弹性成像检查，并以帕斯卡（kPa）单位记录。在阴茎假体植入术中，从右侧和左侧海绵体组织中获取约 0.5×0.5×0.5 cm 的组织样本，并将其送到病理科。对海绵体组织中肌纤维和弹性纤维的面积百分比进行半定量评估（肌纤维与海绵体弹性纤维评分比）。将所有获得的数据相互比较。
海绵体弹性纤维评分数据（分组评分为 1、2 和 3）和海绵体肌纤维百分比数据（分组为 10%、20%、30%……100%）与剪切波弹性成像数据（kPa）进行比较。根据 Kruskal Wallis 检验，结果无统计学意义。海绵体弹性纤维评分与海绵体肌纤维百分比也进行了比较，Kruskal Wallis 检验和 Spearman 相关检验均无统计学意义。
阴茎剪切波弹性成像可用于临床定量评估阴茎平滑肌细胞和弹性纤维的数量，但值得进一步用更多的患者和更具体的病理学准备来研究。
