Thiery M, Kosonen A
Contraception. 1987 Feb;35(2):163-70. doi: 10.1016/s0010-7824(87)80007-0.
Corrosion and dissolution of copper were studied in 136 multisleeved TCu220C models used for up to 158 months. Surface alterations were examined at low magnification. Topography and depth of copper corrosion were evaluated microscopically in cross-sections of the TCu220C devices. Amounts of residual copper were determined by X-ray fluorescence spectrometry. Sleeve and wire corrosion differ in two respects: edge corrosion is typical for tubular copper and the corrosion process is more pronounced in the upper part of multisleeved devices. Despite considerable individual variation, maximum corrosion depth in relation to duration of IUD use is topographically similar for copper sleeves and copper wire. Calcareous deposits reduce both the dissolution and the corrosion of copper but not the contraceptive effectiveness of the TCu220C. Up to 125 months, the loss of copper from deposit-bearing devices amounts on average to 8 micrograms/day as against 23 micrograms/day for TCu220C models without visible coating.
在136个使用长达158个月的多套管式TCu220C型号中研究了铜的腐蚀和溶解情况。以低倍放大观察表面变化。在TCu220C装置的横截面中通过显微镜评估铜腐蚀的形貌和深度。通过X射线荧光光谱法测定残余铜的量。套管和铜丝的腐蚀在两个方面有所不同：边缘腐蚀是管状铜的典型特征，并且在多套管式装置的上部腐蚀过程更为明显。尽管存在相当大的个体差异，但就宫内节育器使用时间而言，铜套管和铜丝的最大腐蚀深度在形貌上相似。钙质沉积物会减少铜的溶解和腐蚀，但不会降低TCu220C的避孕效果。在长达125个月的时间里，有沉积物的装置中铜的损失平均为每天8微克，而没有可见涂层的TCu220C型号为每天23微克。
