肠道-胆囊轴出现：与复发性尿路感染相关。
Gut-bladder axis enters the stage: Implication for recurrent urinary tract infections.
机构信息
Department of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, TX 77030, USA.
Department of Biological Sciences, The University of Texas at Dallas, Richardson, TX 75080, USA.
出版信息
Cell Host Microbe. 2022 Aug 10;30(8):1066-1069. doi: 10.1016/j.chom.2022.07.008.
Abstract
The gut microbiome is a critical modulator of systemic physiology, including infectious disease susceptibility. Although this niche is a reservoir for uropathogenic Escherichia coli, knowledge of its role in urinary tract infections (UTIs) is limited. We discuss two recent studies, Thänert et al. (2022) and Worby et al. (2022), that interrogate the roles of the gut-bladder axis in UTIs.
摘要
肠道微生物组是全身生理学的关键调节剂，包括传染病易感性。尽管这个小生境是尿路致病性大肠杆菌的储存库，但对其在尿路感染 (UTI) 中的作用知之甚少。我们讨论了最近的两项研究，Thänert 等人（2022 年）和 Worby 等人（2022 年），它们探讨了肠道-膀胱轴在 UTI 中的作用。
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