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巴氯芬过量:一个关于医药销售代表的奇特案例。

Baclofen overdose: A curious case of medical sales representative.

作者信息

Gautam Swotantra, Neupane Aakash, Chamlagain Mandita, Pokhrel Sandip, Neupane Durga, Acharya Rochana, Panthi Sagar

机构信息

PGY-1, Resident, Internal Medicine Advent Health Orlando Florida USA.

B.P. Koirala Institute of Health Sciences Dharan Nepal.

出版信息

Clin Case Rep. 2022 Aug 9;10(8):e6230. doi: 10.1002/ccr3.6230. eCollection 2022 Aug.

Abstract

In this case report, a medical sales representative consumed 250 mg of Baclofen out of curiosity. Baclofen has life-threatening complications like seizures, respiratory depression, and coma. A majority of patients recover on symptomatic treatment. Baclofen has a great potential for abuse and overdose; therefore, its use must be strictly monitored.

摘要

在本病例报告中,一名医药销售代表出于好奇服用了250毫克巴氯芬。巴氯芬会引发癫痫、呼吸抑制和昏迷等危及生命的并发症。大多数患者经对症治疗后康复。巴氯芬有很大的滥用和过量服用风险;因此,其使用必须受到严格监测。

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Baclofen Overdose Presenting as Psychosis with Catatonia.以伴有紧张症的精神病形式出现的巴氯芬过量
Indian J Psychol Med. 2017 Sep-Oct;39(5):695-697. doi: 10.4103/IJPSYM.IJPSYM_291_17.
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A nationwide register-based survey of baclofen toxicity.一项基于全国登记系统的巴氯芬毒性调查。
Basic Clin Pharmacol Toxicol. 2015 May;116(5):452-6. doi: 10.1111/bcpt.12344. Epub 2014 Nov 22.
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Baclofen overdose mimicking brain death.巴氯芬过量致脑死亡样表现。
Clin Toxicol (Phila). 2012 Feb;50(2):141-4. doi: 10.3109/15563650.2011.654209. Epub 2012 Jan 31.
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Prescription drug abuse up sharply in the USA.美国处方药滥用情况急剧上升。
Lancet. 2007 May 5;369(9572):1505-6. doi: 10.1016/S0140-6736(07)60690-4.

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