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A Case Report of Baclofen Toxicity in a Pediatric Patient With Normal Kidney Function Successfully Treated With Hemodialysis.一名肾功能正常的儿科患者巴氯芬中毒经血液透析成功治疗的病例报告。
Can J Kidney Health Dis. 2020 Aug 19;7:2054358120950874. doi: 10.1177/2054358120950874. eCollection 2020.
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Role of hemodialysis in baclofen overdose with normal renal function.血液透析在肾功能正常的情况下对巴氯芬过量的作用。
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The GABA B agonist baclofen reduces cigarette consumption in a preliminary double-blind placebo-controlled smoking reduction study.在一项初步的双盲安慰剂对照戒烟研究中，GABA B激动剂巴氯芬可减少香烟消费量。
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Prescription drug abuse up sharply in the USA.美国处方药滥用情况急剧上升。
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巴氯芬过量：一个关于医药销售代表的奇特案例。

Baclofen overdose: A curious case of medical sales representative.

作者信息

Gautam Swotantra, Neupane Aakash, Chamlagain Mandita, Pokhrel Sandip, Neupane Durga, Acharya Rochana, Panthi Sagar

机构信息

PGY-1, Resident, Internal Medicine Advent Health Orlando Florida USA.

B.P. Koirala Institute of Health Sciences Dharan Nepal.

出版信息

Clin Case Rep. 2022 Aug 9;10(8):e6230. doi: 10.1002/ccr3.6230. eCollection 2022 Aug.

DOI:10.1002/ccr3.6230
PMID:35957780
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9361799/
Abstract

In this case report, a medical sales representative consumed 250 mg of Baclofen out of curiosity. Baclofen has life-threatening complications like seizures, respiratory depression, and coma. A majority of patients recover on symptomatic treatment. Baclofen has a great potential for abuse and overdose; therefore, its use must be strictly monitored.

摘要

在本病例报告中，一名医药销售代表出于好奇服用了250毫克巴氯芬。巴氯芬会引发癫痫、呼吸抑制和昏迷等危及生命的并发症。大多数患者经对症治疗后康复。巴氯芬有很大的滥用和过量服用风险；因此，其使用必须受到严格监测。