巴氯芬过量：一个关于医药销售代表的奇特案例。
Baclofen overdose: A curious case of medical sales representative.
作者信息
Gautam Swotantra, Neupane Aakash, Chamlagain Mandita, Pokhrel Sandip, Neupane Durga, Acharya Rochana, Panthi Sagar
机构信息
PGY-1, Resident, Internal Medicine Advent Health Orlando Florida USA.
B.P. Koirala Institute of Health Sciences Dharan Nepal.
出版信息
Clin Case Rep. 2022 Aug 9;10(8):e6230. doi: 10.1002/ccr3.6230. eCollection 2022 Aug.
Abstract
In this case report, a medical sales representative consumed 250 mg of Baclofen out of curiosity. Baclofen has life-threatening complications like seizures, respiratory depression, and coma. A majority of patients recover on symptomatic treatment. Baclofen has a great potential for abuse and overdose; therefore, its use must be strictly monitored.
摘要
在本病例报告中，一名医药销售代表出于好奇服用了250毫克巴氯芬。巴氯芬会引发癫痫、呼吸抑制和昏迷等危及生命的并发症。大多数患者经对症治疗后康复。巴氯芬有很大的滥用和过量服用风险；因此，其使用必须受到严格监测。
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2
Baclofen Toxicity Mimicking Brain Death: A Case Report of a Pediatric Patient.
Pediatr Emerg Care. 2021 Mar 1;37(3):e141-e146. doi: 10.1097/PEC.0000000000002361.
3
A Case Report of Baclofen Toxicity in a Pediatric Patient With Normal Kidney Function Successfully Treated With Hemodialysis.
Can J Kidney Health Dis. 2020 Aug 19;7:2054358120950874. doi: 10.1177/2054358120950874. eCollection 2020.
4
Baclofen Overdose Presenting as Psychosis with Catatonia.
Indian J Psychol Med. 2017 Sep-Oct;39(5):695-697. doi: 10.4103/IJPSYM.IJPSYM_291_17.
5
Baclofen overdose mimicking anoxic encephalopathy: a case report and review of the literature.
Ther Adv Drug Saf. 2017 May;8(5):165-167. doi: 10.1177/2042098617693571. Epub 2017 Feb 1.
6
A nationwide register-based survey of baclofen toxicity.
Basic Clin Pharmacol Toxicol. 2015 May;116(5):452-6. doi: 10.1111/bcpt.12344. Epub 2014 Nov 22.
7
Baclofen overdose mimicking brain death.
Clin Toxicol (Phila). 2012 Feb;50(2):141-4. doi: 10.3109/15563650.2011.654209. Epub 2012 Jan 31.
8
Role of hemodialysis in baclofen overdose with normal renal function.
Indian J Pharmacol. 2011 Nov;43(6):722-3. doi: 10.4103/0253-7613.89835.
9
The GABA B agonist baclofen reduces cigarette consumption in a preliminary double-blind placebo-controlled smoking reduction study.
Drug Alcohol Depend. 2009 Jul 1;103(1-2):30-6. doi: 10.1016/j.drugalcdep.2009.02.014. Epub 2009 Apr 23.
10
Prescription drug abuse up sharply in the USA.
Lancet. 2007 May 5;369(9572):1505-6. doi: 10.1016/S0140-6736(07)60690-4.
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