The effect of cadmium ions on 2,3-bisphosphoglycerate in erythrocytes studied with 31P NMR.
作者信息
Arkowitz R, Hoehn-Berlage M, Gersonde K
出版信息
FEBS Lett. 1987 Jun 8;217(1):21-4. doi: 10.1016/0014-5793(87)81234-6.
PMID:3595843
Abstract
The interaction of cadmium ions with human red blood cell (RBC) 2,3-bisphosphoglycerate (DPG) wasa studied by 31P NMR. 31P NMR spectra and 31P T1 and 31P T2 relaxation times give evidence for cadmium-2,3-bisphosphoglycerate complexation in aqueous solution. 31P NMR spectra indicate the occurrence of a similar complexation in RBC cryolysates. The lag phase (constant polyphosphate level) prior to DPG hydrolysis in incubated red blood cells is lengthened in the presence of cadmium.
摘要
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