Li Jingwei, Shao Jun, Wang Chengdi, Li Weimin
Department of Respiratory and Critical Care Medicine, West China Medical School/West China Hospital, Sichuan University, Chengdu 610041, China.
Precis Clin Med. 2020 Jun;3(2):71-84. doi: 10.1093/pcmedi/pbaa017. Epub 2020 May 28.
An outbreak of coronavirus disease 2019 (COVID-19), a disease caused by a novel pneumonia virus, has affected over 200 countries and regions worldwide. With the increasing number of patients and deaths, WHO have declared it as a global pandemic currently, indicating a third large-scale epidemic coronavirus has appeared since the emergence of severe acute respiratory syndrome coronavirus (SARS) and Middle-East respiratory syndrome (MERS) in the twenty-first century. Considering the great harm it has caused, researchers throughout the world have been chasing to exploit the pathophysiology, characteristics, and potential remedies for COVID-19 to better battle the outbreak. Therefore, the current study revisits advances of the virology, epidemiology, clinical features, therapeutic options, and prevention of COVID-19. The features of asymptomatic carriers are also been explored.
新型冠状病毒肺炎(COVID-19)疫情由一种新型肺炎病毒引起,已影响全球200多个国家和地区。随着患者和死亡人数的不断增加,世界卫生组织目前已宣布其为全球大流行,这表明自21世纪严重急性呼吸综合征冠状病毒(SARS)和中东呼吸综合征(MERS)出现以来,第三种大规模流行的冠状病毒已经出现。鉴于其造成的巨大危害,世界各地的研究人员一直在努力探索COVID-19的病理生理学、特征和潜在治疗方法,以便更好地应对疫情。因此,本研究回顾了COVID-19在病毒学、流行病学、临床特征、治疗选择和预防方面的进展。同时也探讨了无症状携带者的特征。