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沙特阿拉伯王国类风湿性关节炎患者中高血压及其相关危险因素的患病率

Prevalence of Hypertension and Its Associated Risk Factors Among Patients with Rheumatoid Arthritis in the Kingdom of Saudi Arabia.

作者信息

Al-Ahmari Abdullah K

机构信息

Department of Clinical Pharmacy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Riyadh, Saudi Arabia.

出版信息

Int J Gen Med. 2022 Aug 8;15:6507-6517. doi: 10.2147/IJGM.S370956. eCollection 2022.

Abstract

PURPOSE

Data regarding hypertension prevalence among patients with rheumatoid arthritis in Saudi Arabia are scarce. This study was aimed at estimating the prevalence of hypertension and its associated risk factors among patients with rheumatoid arthritis in Saudi Arabia.

PATIENTS AND METHODS

This was a cross-sectional study of adult patients with rheumatoid arthritis who presented at the OPD of two major hospitals in Riyadh city. Patient information such as demographic characteristics, comorbidities, drug use, and other clinical data were captured through medical record review and supplemented by patient interviews. Multivariate logistic regression was used to identify the significant factors for hypertension.

RESULTS

The prevalence of hypertension was found in 32.35% of the 1490 rheumatoid arthritis patients who participated in our study. Logistic regression analyses revealed that advanced age, female sex, low education level, unemployment, smoking, and consulting with physicians less than two times within the past 12 months were risk factors for increased hypertension prevalence among patients with rheumatoid arthritis. A significantly higher risk of hypertension was observed among RA patients with obesity, diabetes, hyperlipidemia, cancer, kidney disease, osteoporosis, and Parkinson's disease than among patients without these comorbidities.

CONCLUSION

Hypertension is highly prevalent among patients with rheumatoid arthritis, and advanced age, sex, low educational level, unemployment, smoking, and comorbidities are risk factors for increased hypertension prevalence.

摘要

目的

沙特阿拉伯类风湿关节炎患者高血压患病率的数据匮乏。本研究旨在估计沙特阿拉伯类风湿关节炎患者中高血压的患病率及其相关危险因素。

患者与方法

这是一项对利雅得市两家主要医院门诊就诊的成年类风湿关节炎患者进行的横断面研究。通过病历审查获取患者的人口统计学特征、合并症、用药情况及其他临床数据等信息,并辅以患者访谈。采用多因素逻辑回归分析确定高血压的显著相关因素。

结果

在参与本研究的1490例类风湿关节炎患者中,高血压患病率为32.35%。逻辑回归分析显示,高龄、女性、低教育水平、失业、吸烟以及在过去12个月内就诊次数少于两次是类风湿关节炎患者高血压患病率增加的危险因素。与无这些合并症的患者相比,患有肥胖症、糖尿病、高脂血症、癌症、肾脏疾病、骨质疏松症和帕金森病的类风湿关节炎患者患高血压的风险显著更高。

结论

高血压在类风湿关节炎患者中高度流行,高龄、性别、低教育水平、失业、吸烟和合并症是高血压患病率增加的危险因素。

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