Wang Yuanyuan, Shao Hui, Li Zuomin, Xu Wenying, Zhang Rui, Hu Zhishuo, Zou Jing
Department of Stomatology, Wuhan First Hospital, No.215 Zhongshan Avenue, Qiaokou District, Wuhan, 430000 Hubei People's Republic of China.
Department of Pediatrics, Wuhan First Hospital, Wuhan, 430000 Hubei People's Republic of China.
Iran J Sci Technol Trans A Sci. 2022;46(4):1171-1176. doi: 10.1007/s40995-022-01338-x. Epub 2022 Aug 8.
This study aims to explore the clinical characteristics of the patients with novel coronavirus pneumonia (COVID-19) during rehabilitation. One hundred and twelve confirmed patients were enrolled, while 72 were females (64.3%) and 40 were males (35.7%). The age of the patients was 51.63 ± 4.07 years old. Those patients were divided into mild group, moderate group and severe group based on lesion volume and proportion of total lesion on CT images. The age, gender, past medical history, finger pulse oxygen (SPO2), heart rate (HR) and body temperature and other clinical characteristics of patients were collected. Lesion volume was measured by CT. Compared with mild group, age, lesion volume and total lesion proportion in moderate group were significantly higher. Age, lesion volume and total lesion proportion in severe group were also higher than those in moderate group. Age and past medical history were the risk factors for the lesion volume of COVID-19. Older the patient has larger CT lesion range ( = 0.232, = 0.045). Without past medical history or combination of post-medical history, the COVID-19 patients had smaller CT lesion ranges, and the history of previous cardiovascular disease and pulmonary disease was important risk factors for the larger CT lesion ranges. The patients who were older or combined with chronic diseases, especially cardiovascular diseases, respiratory disease and diabetes, tended to have the larger lesions. Age and past medical history of patients with COVID-19 period are significantly related to the lesion volume and total lesion proportion on CT images.
本研究旨在探讨新型冠状病毒肺炎（COVID-19）患者康复期的临床特征。共纳入112例确诊患者，其中女性72例（64.3%），男性40例（35.7%）。患者年龄为51.63±4.07岁。根据CT图像上的病灶体积和总病灶比例将这些患者分为轻症组、中症组和重症组。收集患者的年龄、性别、既往病史、指脉氧（SPO2）、心率（HR）和体温等临床特征。通过CT测量病灶体积。与轻症组相比，中症组的年龄、病灶体积和总病灶比例显著更高。重症组的年龄、病灶体积和总病灶比例也高于中症组。年龄和既往病史是COVID-19病灶体积的危险因素。患者年龄越大，CT病灶范围越大（=0.232，=0.045）。无既往病史或合并既往病史的COVID-19患者CT病灶范围较小，既往心血管疾病和肺部疾病史是CT病灶范围较大的重要危险因素。年龄较大或合并慢性病，尤其是心血管疾病、呼吸系统疾病和糖尿病的患者，往往病灶较大。COVID-19患者的年龄和既往病史与CT图像上的病灶体积和总病灶比例显著相关。
