• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

从伊朗伊斯法罕患者中分离出的菌株的抗生素耐药模式。

Antibiotic resistance pattern of strains isolated from patients in Isfahan, Iran.

作者信息

Sadeghi Hajarsadat, Narimani Tahmineh, Tabesh Elham, Shafiee Fatemeh, Soltani Rasool

机构信息

Students Research Committee, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.

Department of Microbiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

出版信息

J Res Med Sci. 2022 May 30;27:39. doi: 10.4103/jrms.jrms_829_21. eCollection 2022.

DOI:10.4103/jrms.jrms_829_21
PMID:35968205
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9374139/
Abstract

BACKGROUND

The objective of this study was to evaluate the antibiotic resistance pattern of strains isolated from patients in Isfahan province.

MATERIALS AND METHODS

Gastric antrum biopsy specimens of patients undergoing endoscopy were cultured. The samples with the growth of underwent antibiotic susceptibility test by disk diffusion method.

REAULTS

Of 96 samples, 50 samples (53%) were positive for . The rates of antibiotic resistance were as follows: amoxicillin, 6%; azithromycin, 20%; furazolidone, 22%; levofloxacin, 16%; metronidazole, 20%; rifampin, 12%; and tetracycline, 22%.

CONCLUSION

strains in our area have high rates of resistance to azithromycin, levofloxacin, metronidazole, tetracycline, and furazolidone.

摘要

背景

本研究的目的是评估从伊斯法罕省患者中分离出的菌株的抗生素耐药模式。

材料与方法

对接受内镜检查患者的胃窦活检标本进行培养。对有生长的样本采用纸片扩散法进行抗生素敏感性试验。

结果

96份样本中,50份(53%)检测呈阳性。抗生素耐药率如下:阿莫西林6%;阿奇霉素20%;呋喃唑酮22%;左氧氟沙星16%;甲硝唑20%;利福平12%;四环素22%。

结论

我们地区的菌株对阿奇霉素、左氧氟沙星、甲硝唑、四环素和呋喃唑酮有较高的耐药率。

相似文献

1
Antibiotic resistance pattern of strains isolated from patients in Isfahan, Iran.从伊朗伊斯法罕患者中分离出的菌株的抗生素耐药模式。
J Res Med Sci. 2022 May 30;27:39. doi: 10.4103/jrms.jrms_829_21. eCollection 2022.
2
Resistance pattern of Helicobacter pylori strains to clarithromycin, metronidazole, and amoxicillin in Isfahan, Iran.伊朗伊斯法罕幽门螺杆菌菌株对克拉霉素、甲硝唑和阿莫西林的耐药模式
J Res Med Sci. 2013 Dec;18(12):1056-60.
3
[Antibiotic resistance of Helicobacter pylori clinical isolates in Hebei Province].河北省幽门螺杆菌临床分离株的抗生素耐药性
Zhonghua Yi Xue Za Zhi. 2016 Jan 26;96(4):270-2. doi: 10.3760/cma.j.issn.0376-2491.2016.04.008.
4
Primary Antibiotic Resistance to Helicobacter pylori Strains Isolated From Children in Northern Iran: A Single Center Study.伊朗北部儿童分离出的幽门螺杆菌菌株的原发性抗生素耐药性:一项单中心研究
Iran J Pediatr. 2015 Dec;25(6):e2661. doi: 10.5812/ijp.2661. Epub 2015 Dec 23.
5
Antibiotic susceptibility of Helicobacter pylori strains isolated from Iranian children: High frequency of A2143G point mutation associated with clarithromycin resistance.从伊朗儿童中分离的幽门螺杆菌菌株的抗生素敏感性:与克拉霉素耐药相关的 A2143G 点突变的高频率。
J Glob Antimicrob Resist. 2017 Sep;10:131-135. doi: 10.1016/j.jgar.2017.04.011. Epub 2017 Jul 15.
6
Primary Antibiotic Resistance of Helicobacter pylori in China.中国幽门螺杆菌的原发性抗生素耐药性
Dig Dis Sci. 2017 May;62(5):1146-1154. doi: 10.1007/s10620-017-4536-8. Epub 2017 Mar 17.
7
In vitro antimicrobial susceptibility of Helicobacter pylori to nine antibiotics currently used in Central Italy.意大利中部目前使用的九种抗生素对幽门螺杆菌的体外抗菌敏感性
Scand J Gastroenterol. 2016 Mar;51(3):263-9. doi: 10.3109/00365521.2015.1092577. Epub 2015 Oct 7.
8
Broad spectrum resistance in Helicobacter pylori isolated from gastric biopsies of patients with dyspepsia in Cameroon and efflux-mediated multiresistance detection in MDR isolates.在喀麦隆消化不良患者的胃活检中分离出的幽门螺杆菌的广谱耐药性和 MDR 分离株中流出介导的多药耐药性检测。
BMC Infect Dis. 2019 Oct 22;19(1):880. doi: 10.1186/s12879-019-4536-8.
9
Increase in resistance rates of H. pylori isolates to metronidazole and tetracycline--comparison of three 3-year studies.幽门螺杆菌分离株对甲硝唑和四环素耐药率的增加——三项为期 3 年的研究比较。
Arch Iran Med. 2010 May;13(3):177-87.
10
ANTIBIOTIC RESISTANCE SURVEILLANCE OF HELICOBACTER PYLORI AT THE BIOBÍO REGION (CHILE) IN A DECADE.十年间智利比奥比奥地区幽门螺杆菌的抗生素耐药性监测
Arq Gastroenterol. 2019 Oct-Dec;56(4):361-366. doi: 10.1590/S0004-2803.201900000-72.

引用本文的文献

1
Challenges and Prospects for Eradication of : Targeting Virulence Factors, Metabolism, and Vaccine Innovation.根除的挑战与前景:靶向毒力因子、代谢及疫苗创新
Pathogens. 2025 Jun 21;14(7):619. doi: 10.3390/pathogens14070619.
2
Antibiotic resistance in Helicobacter pylori: From potential biomolecular mechanisms to clinical practice.幽门螺杆菌的抗生素耐药性:从潜在的生物分子机制到临床实践。
J Clin Lab Anal. 2023 Apr;37(7):e24885. doi: 10.1002/jcla.24885. Epub 2023 Apr 23.

本文引用的文献

1
An Updated Systematic Review and Meta-Analysis on the Antibiotic Resistance in Iran (2010-2020).伊朗(2010-2020 年)抗生素耐药性的更新系统评价和荟萃分析。
Microb Drug Resist. 2020 Oct;26(10):1186-1194. doi: 10.1089/mdr.2020.0088. Epub 2020 Apr 30.
2
Increased Incidence and Mortality of Gastric Cancer in Immigrant Populations from High to Low Regions of Incidence: A Systematic Review and Meta-Analysis.移民人群中胃癌发病率和死亡率的增加:从高到低发病地区的系统评价和荟萃分析。
Clin Gastroenterol Hepatol. 2020 Feb;18(2):347-359.e5. doi: 10.1016/j.cgh.2019.05.032. Epub 2019 May 30.
3
High primary resistance to metronidazole and levofloxacin, and a moderate resistance to clarithromycin in isolated from Karnataka patients.从卡纳塔克邦患者中分离出的菌株对甲硝唑和左氧氟沙星具有较高的原发性耐药性,对克拉霉素具有中度耐药性。
Gut Pathog. 2019 May 13;11:21. doi: 10.1186/s13099-019-0305-x. eCollection 2019.
4
Eradication of in Iran: A Review.伊朗的根除:一项综述。
Middle East J Dig Dis. 2018 Jan;10(1):5-17. doi: 10.15171/mejdd.2017.84. Epub 2017 Sep 21.
5
Management of Helicobacter pylori infection-the Maastricht V/Florence Consensus Report.幽门螺杆菌感染的管理——马斯特里赫特 V/佛罗伦萨共识报告。
Gut. 2017 Jan;66(1):6-30. doi: 10.1136/gutjnl-2016-312288. Epub 2016 Oct 5.
6
Diagnosis and management of gastric dysplasia.胃发育异常的诊断与管理
Korean J Intern Med. 2016 Mar;31(2):201-9. doi: 10.3904/kjim.2016.021. Epub 2016 Feb 26.
7
Resistance pattern of Helicobacter pylori strains to clarithromycin, metronidazole, and amoxicillin in Isfahan, Iran.伊朗伊斯法罕幽门螺杆菌菌株对克拉霉素、甲硝唑和阿莫西林的耐药模式
J Res Med Sci. 2013 Dec;18(12):1056-60.
8
Helicobacter pylori isolates recovered from gastric biopsies of patients with gastro-duodenal pathologies in Cameroon: current status of antibiogram.从喀麦隆胃十二指肠疾病患者胃活检中分离出的幽门螺杆菌菌株:药敏谱现状
Trop Med Int Health. 2008 Jun;13(6):848-54. doi: 10.1111/j.1365-3156.2008.02062.x. Epub 2008 Mar 31.
9
Azithromycin in one week quadruple therapy for H pylori eradication in Iran.阿奇霉素用于伊朗幽门螺杆菌根除的一周四联疗法。
World J Gastroenterol. 2006 Jul 28;12(28):4553-6. doi: 10.3748/wjg.v12.i28.4553.
10
Diagnosis of Helicobacter pylori infection in patients with bleeding ulcer disease: rapid urease test and histology.出血性溃疡病患者幽门螺杆菌感染的诊断:快速尿素酶试验和组织学检查。
Rev Esp Enferm Dig. 2004 Jun;96(6):395-8; 398-401. doi: 10.4321/s1130-01082004000600005.