Glickman Urological & Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.
Glickman Urological & Kidney Institute, Cleveland Clinic, Cleveland, OH, USA.
Eur Urol. 2022 Nov;82(5):551-558. doi: 10.1016/j.eururo.2022.07.017. Epub 2022 Aug 13.
Partial prostatectomy has been described as an alternative to focal therapy for the management of localized low- and intermediate-risk prostate cancer.
To describe early outcomes and technique for single-port (SP) transvesical partial prostatectomy.
DESIGN, SETTING, AND PARTICIPANTS: A retrospective analysis was performed for nine patients with low-volume, localized, low- to intermediate-risk prostate cancer (Gleason ≤7) undergoing SP transvesical partial prostatectomy replicating the inclusion criteria for focal therapy by a single surgeon from November 2020 to March 2022.
The daVinci SP access port was inserted percutaneously into the bladder and pnuemovesicum was achieved. The camera, robotic instruments, assistant port, and flexible suction tubing were introduced through the access port. The Koelis transrectal ultrasound with preoperative prostate magnetic resonance imaging fusion was used for intraoperative guidance.
Demographic information, intraoperative variables, and postoperative outcomes were collected in an institutional review board-approved database, and a descriptive statistical analysis was performed.
All cases were completed without requiring extra ports or conversion. No intraoperative complications were noted, and all patients were discharged on the day of surgery. Pathology showed Gleason scores of 3 + 3 = 6 in one case, 3 + 4 = 7 in seven cases, and 4 + 3 = 7 in one case, all with negative intraoperative margin assessment. At 6 wk, the median prostate-specific antigen was 0.5 and the median Sexual Health Inventory for Men score was 17.5 from 23 preoperatively. All patients were continent at 6 wk. The limitations include a small number of patients, short follow-up, and single-surgeon experience.
We demonstrated the feasibility of the SP robotic transvesical partial prostatectomy. Early functional outcomes show impressive time to continence and erectile function. Continued follow-up will evaluate long-term oncologic outcomes.
We performed partial prostatectomies in selected patients as an alternative to focal therapy using a novel transvesical single-port approach. Our approach was safe and feasible, with fewer complications and promising initial return to continence and erectile function.
部分前列腺切除术已被描述为局部低危和中危前列腺癌的一种替代选择,用于焦点治疗。
描述单端口(SP)经膀胱前列腺部分切除术的早期结果和技术。
设计、地点和参与者:对 2020 年 11 月至 2022 年 3 月期间由一位外科医生根据焦点治疗的纳入标准进行的 9 例低体积、局限性、低至中危前列腺癌(Gleason ≤7)患者的回顾性分析。患者接受了 SP 经膀胱前列腺部分切除术。通过经皮插入 daVinci SP 接入端口并实现了 pneumovesicum。将摄像头、机器人器械、助手端口和柔性抽吸管通过接入端口引入。使用术前前列腺磁共振成像融合的 Koelis 经直肠超声进行术中引导。
所有病例均无需额外端口或转换即可完成。术中无并发症发生,所有患者均在手术当天出院。病理学检查显示 1 例为 3+3=6,7 例为 3+4=7,1 例为 4+3=7,所有病例均为术中边缘评估阴性。6 周时,中位前列腺特异性抗原为 0.5,23 例术前中位男性健康调查-性健康问卷为 17.5。所有患者在 6 周时均能控制尿失禁。局限性包括患者数量少、随访时间短和单外科医生经验。
我们证明了 SP 机器人经膀胱前列腺部分切除术的可行性。早期的功能结果显示出令人印象深刻的控尿和勃起功能恢复时间。持续随访将评估长期肿瘤学结果。
我们为选定的患者实施了部分前列腺切除术,作为焦点治疗的替代选择,采用了一种新的经膀胱单端口方法。我们的方法安全可行,并发症较少,并且有恢复控尿和勃起功能的良好前景。