The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine/Research Center of Neurobiology, Shanxi University of Chinese Medicine, Jinzhong 030619, China.
Department of Physiology, Shanxi Medical University, Taiyuan 030001, China.
Biomed Res Int. 2022 Aug 6;2022:7799243. doi: 10.1155/2022/7799243. eCollection 2022.
Autophagy plays a key role in ischemic stroke, but its mechanism remains to be elucidated. In order to explore the effect of autophagy on ischemic stroke, bibliometric analysis and view tools are used to identify the directions of the global research trends and construct full view of the autophagy in ischemic stroke from 2006 to 2022. The research hotspots of autophagy related to ischemic stroke are visually analyzed and generated various visual maps to display publications, authors, sources, countries, organizations, and keywords. By bibliometric analysis, it can be seen that the investigations of autophagy in ischemic stroke is focused on both brain injury and neuroprotection. The impact of a variety of inflammatory factors and signaling pathways on autophagy following an ischemic stroke is also studied. Autophagy plays an important role in all phases of ischemic stroke. It is of great significance to guide the development of treatment plans for ischemic stroke.
自噬在缺血性卒中中发挥着关键作用,但其中的作用机制仍有待阐明。为了探究自噬对缺血性卒中的影响,本研究采用文献计量分析和视图工具,确定了全球研究趋势的方向,并构建了 2006 年至 2022 年自噬与缺血性卒中关系的全景图。本研究对视相关的自噬与缺血性卒中的研究热点进行了可视化分析,并生成了各种可视化图谱,以展示出版物、作者、来源、国家、组织和关键词。通过文献计量分析,可以看出自噬在缺血性卒中中的研究主要集中在脑损伤和神经保护两个方面。还研究了多种炎症因子和信号通路对缺血性卒中后自噬的影响。自噬在缺血性卒中的各个阶段都发挥着重要作用,这对指导缺血性卒中治疗方案的制定具有重要意义。