手部湿疹的危险因素：一项针对 900 名受试者的基于人群的研究。
Risk factors of hand eczema: A population-based study among 900 subjects.
机构信息
Department of Dermatology, University Hospital of Oulu, Oulu, Finland and Medical Research Center, PEDEGO Research Group, University of Oulu, Oulu, Finland.
Northern Finland Birth Cohorts, Arctic Biobank, Infrastructure for Population Studies, Faculty of Medicine, University of Oulu, Oulu, Finland.
出版信息
Contact Dermatitis. 2022 Dec;87(6):485-491. doi: 10.1111/cod.14205. Epub 2022 Aug 29.
BACKGROUND
Many risk factors such as atopic dermatitis (AD) have shown to associate with hand eczema (HE). However, studies concerning other atopic diseases, parental or longitudinal risk factors of HE are scarce.
OBJECTIVES
To examine the association between HE and atopic diseases, parental factors, environmental factors (keeping animals, exposure to moulds) and lifestyle factors (obesity, tobacco smoking, alcohol consumption and physical activity) at population level.
METHODS
Subjects belonging to the Northern Finland Birth Cohort 1966 Study (NFBC1966) (n = 6830) answered a comprehensive health questionnaire. The data was completed with parental information.
RESULTS
HE was reported in 900 (13.3%) individuals. All atopic diseases, parental allergy, female gender and obesity increased the risk of HE whereas physical activity decreased the risk of HE. A statistically significant association was not found between HE and tobacco smoking or alcohol consumption.
CONCLUSIONS
All atopic diseases, not only AD, seem to have influence on the presence of HE. In addition, parental and environmental factors associated with HE.
背景
许多风险因素，如特应性皮炎（AD），已被证明与手部湿疹（HE）有关。然而，关于其他特应性疾病、父母或纵向风险因素的研究还很少。
目的
在人群水平上，研究 HE 与特应性疾病、父母因素、环境因素（饲养动物、接触霉菌）和生活方式因素（肥胖、吸烟、饮酒和体力活动）之间的关联。
方法
属于芬兰北部出生队列 1966 研究（NFBC1966）（n=6830）的受试者回答了一份综合健康问卷。这些数据是通过父母的信息来完成的。
结果
报告了 900 例（13.3%）HE。所有特应性疾病、父母过敏、女性和肥胖都会增加 HE 的风险，而体力活动则降低了 HE 的风险。HE 与吸烟或饮酒之间没有统计学上显著的关联。
结论
所有特应性疾病，而不仅仅是 AD，似乎都对 HE 的存在有影响。此外，还存在与 HE 相关的父母和环境因素。
Zotero 插件