Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Instituto de Investigación Sanitaria Hospital Gregorio Marañón, Madrid, Spain.
Euro Surveill. 2022 Aug;27(33). doi: 10.2807/1560-7917.ES.2022.27.33.2200598.
A monkeypox virus (MPXV) outbreak has been ongoing worldwide since May 2022. The role of specimens other than skin lesions for MPXV diagnosis is unknown. We evaluated 140 different clinical specimens by real-time PCR. The highest positivity rates (97%) were from skin lesions of any part of the body, followed by plasma, pharyngeal and anal swabs. Testing specimens from multiple sites may improve the sensitivity and reduce false-negative test results.
自 2022 年 5 月以来，猴痘病毒（MPXV）疫情在全球范围内持续蔓延。目前尚不清楚除皮损以外的其他标本在 MPXV 诊断中的作用。我们通过实时 PCR 评估了 140 种不同的临床标本。阳性率最高的标本（97%）来自身体任何部位的皮损，其次是血浆、咽拭子和肛拭子。对多个部位的标本进行检测，可能会提高检测的敏感性，减少假阴性的检测结果。
