Sharma Pragya, Basu Saurav, Mishra Suruchi, Mundeja Nutan, Charan B S, Singh Gautam, Singh Mongjam M
Community Medicine, Maulana Azad Medical College, New Delhi, IND.
Indian Institute of Public Health-Delhi, Public Health Foundation of India, New Delhi, IND.
Cureus. 2022 Jul 17;14(7):e26936. doi: 10.7759/cureus.26936. eCollection 2022 Jul.
To ascertain the COVID-19 vaccination acceptance and the factors contributing to vaccine hesitancy and vaccine confidence in the adult population, and the intention for vaccination of their children.
This cross-sectional analysis reports the ancillary results of a population-based SARS-CoV-2 serosurvey conducted in Delhi, India, from September 24 to October 14, 2021. Data were collected from 20312 adult participants through a multistage sampling method from all the 274 wards in the 11 districts of the national capital territory region.
We enrolled 12093 (59.3%) females and 8219 (40.5%) male participants with mean (SD) age of 40.3 (14.6) years. The vaccine acceptance rate in the participants was 67.7% (95% CI 67.1, 68.4), with 6031 (43.8%) having received one dose and 7727 (56.2%) having received two vaccine doses. On adjusted analysis, lack of vaccine acceptance was independently associated with female gender aOR 1.15 (95% CI 1.1, 1.23), younger age-group (18-49 years) aOR 1.85 (95% CI 1.71, 2.0), low educational status aOR 1.88 (95% CI 1.77, 2.0), in those with no history of COVID-19 aOR 1.81 (95% CI 1.69, 1.95), non-healthcare workers aOR 2.1 (95% CI 1.7, 2.53), and in the absence of hypertension comorbidity aOR 1.22 (1.1, 1.38). Lack of awareness of COVID-19 vaccines, including doubts on vaccine efficacy and long-term safety, were primary drivers of vaccine hesitancy in the unvaccinated subgroup. Only 35.6% participants reported a positive intention to vaccinate their children.
One in three adults lacked vaccine acceptance. High prevalence of delay in second dose vaccination was also observed.
确定新冠病毒疫苗在成年人群中的接种接受情况、导致疫苗犹豫和疫苗信心的因素，以及他们为子女接种疫苗的意愿。
本横断面分析报告了2021年9月24日至10月14日在印度德里进行的一项基于人群的新冠病毒血清学调查的辅助结果。通过多阶段抽样方法，从国家首都辖区11个区的274个病房中收集了20312名成年参与者的数据。
我们纳入了12093名（59.3%）女性和8219名（40.5%）男性参与者，平均（标准差）年龄为40.3（14.6）岁。参与者的疫苗接种接受率为67.7%（95%置信区间67.1, 68.4），其中6031人（43.8%）接种了一剂，7727人（56.2%）接种了两剂。经调整分析，未接受疫苗接种与女性性别独立相关，调整后比值比为1.15（95%置信区间1.1, 1.23）；年龄较小组（18 - 49岁），调整后比值比为1.85（95%置信区间1.71, 2.0）；教育程度低，调整后比值比为1.88（95%置信区间1.77, 2.0）；无新冠病毒感染史者，调整后比值比为1.81（95%置信区间1.69, 1.95）；非医护人员，调整后比值比为2.1（95%置信区间1.7, 2.53）；无高血压合并症者，调整后比值比为1.22（1.1, 1.38）。对新冠病毒疫苗缺乏认识，包括对疫苗效力和长期安全性的怀疑，是未接种疫苗亚组中疫苗犹豫的主要驱动因素。只有35.6%的参与者表示有积极为子女接种疫苗的意愿。
三分之一的成年人未接受疫苗接种。还观察到第二剂疫苗接种延迟的高发生率。
