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COVID-19 疫苗接种意愿和犹豫:对 COVID-19 疫苗益处的不信任是医护人员疫苗犹豫的主要驱动因素;印度北部的一项横断面研究。

COVID-19 vaccination intention and hesitancy: Mistrust on COVID-19 vaccine benefit a major driver for vaccine hesitancy among healthcare workers; a cross-sectional study in North India.

机构信息

MSc Nursing, Public health Nursing, PGIMER, Chandigarh.

BSc Nursing, Bel-Air College of Nursing Panchgani.

出版信息

J Prev Med Hyg. 2022 Jul 31;63(2):E219-E230. doi: 10.15167/2421-4248/jpmh2022.63.2.1952. eCollection 2022 Jun.

DOI:10.15167/2421-4248/jpmh2022.63.2.1952
PMID:35968070
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9351420/
Abstract

BACKGROUND

The advent of an effective novel COVID-19 vaccine could extinguish the current devastating pandemic but the vaccine hesitancy is a hurdle for the public health system, so this study estimated the COVID-19 vaccination intention and hesitancy among the healthcare workers, the priority target group for the COVID-19 vaccination in India.

METHODS

A web-based cross-sectional survey was conducted among the healthcare workers in Chandigarh, a union territory in North India, using a Snowball sampling technique. A total of 403 healthcare workers participated in the study between 2 and 25 January 2021. The primary data collected were the intention to get vaccinated against the available COVID-19 vaccine and the concerns regarding the new vaccines. The attitude towards novel COVID-19 vaccine was assessed using developed Vaccine attitude examination scale. These questionnaire, which were delivered via WhatsApp, was filled by the participants over Google forms.

RESULTS

Among the 403 respondents surveyed, the majority (54.6%) reported they were definitely intended to get vaccinated against COVID-19, however, 7% expressed a resistance for inoculation with COVID-19 vaccination. The perceived susceptibility (aOR = 0.511, CI 0.265-0.987) and severity of COVID-19 infection (aOR = 0.551 CI 0.196-0.704) and not being concerned about the efficacy of new COVID-19 vaccines (aOR = 0.702 CI 1.109-26.55) were found to have the highest significant odds of intention to take the COVID-19 vaccine. The majority (62%) were concerned about the safety of the vaccine, in terms of side-effects, quality control, and doubted efficacy of the vaccine. The mistrust of the benefits of the vaccine is a significant predictor for vaccine hesitancy among the healthcare workers (aOR = 5.205 CI 3.106-8.723).

CONCLUSION

Therefore, strategic communication and vaccine-acceptance programs should be formulated in order to combat the prevailing mistrust on the vaccine safety and efficacy and attain effective coverage to gain herd immunity.

摘要

背景

一种有效的新型 COVID-19 疫苗的出现可能会终结当前这场毁灭性的大流行,但疫苗犹豫是公共卫生系统面临的一个障碍,因此本研究旨在评估印度医疗保健工作者对 COVID-19 疫苗的接种意愿和犹豫。

方法

本研究于 2021 年 1 月 2 日至 25 日采用滚雪球抽样技术在印度北部联邦属地昌迪加尔的医疗保健工作者中进行了一项基于网络的横断面调查。共有 403 名医疗保健工作者参与了这项研究。主要收集的是对现有 COVID-19 疫苗进行接种的意愿和对新疫苗的担忧。采用自行设计的疫苗态度检查表评估对新型 COVID-19 疫苗的态度。这些通过 WhatsApp 发送的问卷由参与者在 Google 表单上填写。

结果

在接受调查的 403 名受访者中,大多数(54.6%)表示他们肯定打算接种 COVID-19 疫苗,但有 7%表示对接种 COVID-19 疫苗有抵触。感知易感性(OR = 0.511,CI 0.265-0.987)和 COVID-19 感染的严重程度(OR = 0.551,CI 0.196-0.704)以及对新型 COVID-19 疫苗疗效不担忧(OR = 0.702,CI 1.109-26.55)被发现对接种 COVID-19 疫苗的意愿具有最高的显著优势比。大多数(62%)对疫苗的安全性表示担忧,主要是副作用、质量控制方面,对疫苗的有效性表示怀疑。对疫苗益处的不信任是医疗保健工作者疫苗犹豫的一个重要预测因素(OR = 5.205,CI 3.106-8.723)。

结论

因此,应制定战略沟通和疫苗接种接受方案,以应对疫苗安全性和有效性方面普遍存在的不信任,并实现有效的疫苗接种覆盖率,以获得群体免疫。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/519d/9351420/26aa05fc83c8/jpmh-2022-02-e219-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/519d/9351420/d1237f0264ab/jpmh-2022-02-e219-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/519d/9351420/26aa05fc83c8/jpmh-2022-02-e219-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/519d/9351420/d1237f0264ab/jpmh-2022-02-e219-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/519d/9351420/26aa05fc83c8/jpmh-2022-02-e219-g002.jpg

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