Drejza Michalina Anna, Rylewicz Katarzyna, Majcherek Ewa, Gross-Tyrkin Katarzyna, Mizgier Małgorzata, Plagens-Rotman Katarzyna, Wójcik Małgorzata, Panecka-Mysza Katarzyna, Pisarska-Krawczyk Magdalena, Kędzia Witold, Jarząbek-Bielecka Grażyna
Specialty Trainee in Obstetrics and Gynaecology, Princess Alexandra Hospital NHS Trust, Harlow CM20 1QX, UK.
Medical University of Warsaw, 02-091 Warsaw, Poland.
Antioxidants (Basel). 2022 Jul 28;11(8):1477. doi: 10.3390/antiox11081477.
Oxidative stress has been implicated in many diseases, including reproductive and pregnancy disorders, from subfertility to maternal vascular disease or preterm labour. There is, however, discrepancy within the standardized markers of oxidative stress in obstetrics and gynaecology in clinical studies. This review aims to present the scope of markers used between 2012 and 2022 to describe oxidative stress with regard to reproduction, pregnancy, and pregnancy-related issues. Despite the abundance of evidence, there is no consensus on the set of standardised markers of oxidative stress which poses a challenge to achieve universal consensus in order to appropriately triangulate the results.
氧化应激与许多疾病有关，包括生殖和妊娠疾病，从生育力低下到母体血管疾病或早产。然而，在临床研究中，妇产科氧化应激的标准化标志物存在差异。本综述旨在介绍2012年至2022年间用于描述生殖、妊娠及妊娠相关问题中氧化应激的标志物范围。尽管有大量证据，但对于氧化应激的标准化标志物组仍未达成共识，这给达成普遍共识以适当整合结果带来了挑战。
