母乳喂养能预防儿童多系统炎症综合征（MIS-C）吗？一项初步研究。
Can Breastfeeding Protect from Multi-System Inflammatory Syndrome in Children (MIS-C)? A Preliminary Study.
作者信息
Rodríguez-Fanjul Xavier, Verd Sergio, Brio Sonia
机构信息
Intensive Care Unit, Department of Paediatrics, Germans Trias i Pujol Hospital, Canyet Rd., 08916 Badalona, Spain.
Paediatric Unit, Department of Primary Care, Matamusinos Street, 07013 Palma de Mallorca, Spain.
出版信息
Children (Basel). 2022 Aug 2;9(8):1160. doi: 10.3390/children9081160.
BACKGROUND
Breastfeeding prevents Kawasaki disease (KD), as well as several autoimmune disorders. Since there is an overlap between the Multi-System Inflammatory Syndrome in children following SARS-CoV-2 infection (MIS-C) and KD, this case series aims to analyze the association between breastfeeding and MIS-C.
METHODS
A series of 16 cases of children with MIS-C admitted to three pediatric facilities between January 2021 and May 2022 were conducted. Breastfeeding rate was estimated through the Brief Breastfeeding and Milk Expression Recall Survey.
RESULTS
Out of 16 children, 9 (56%) had been breastfed at birth.
DISCUSSION
Our breastfeeding rate is below the median Spanish rate for initial breastfeeding. These findings do not clearly support the hypothesis that breastfeeding might prevent MIS-C.
CONCLUSION
Contrary to the role of breastfeeding in KD prevention, our case series cannot answer with certainty the question about whether or not breastfeeding does protect children against MIS-C. These findings require confirmation in larger studies.
背景
母乳喂养可预防川崎病（KD）以及多种自身免疫性疾病。由于严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染后儿童多系统炎症综合征（MIS-C）与KD之间存在重叠，本病例系列旨在分析母乳喂养与MIS-C之间的关联。
方法
对2021年1月至2022年5月期间在三家儿科机构收治的16例MIS-C患儿进行了研究。通过简短母乳喂养和挤奶回忆调查评估母乳喂养率。
结果
16名儿童中，9名（56%）出生时接受过母乳喂养。
讨论
我们的母乳喂养率低于西班牙初乳喂养率的中位数。这些发现并未明确支持母乳喂养可能预防MIS-C这一假设。
结论
与母乳喂养在预防KD中的作用相反，我们的病例系列无法确定地回答母乳喂养是否确实能保护儿童免受MIS-C影响这一问题。这些发现需要在更大规模的研究中得到证实。
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