Tang Si-Jia, Lee Heejin, Cui Tiantian, Lee Jae Min, Ahn Ji Young, Lee Sua, Kim Saeyoon
Graduate School, Yeungnam University College of Medicine, Daegu 42415, Korea.
Department of Pediatrics, Yeungnam University Medical Center, Daegu 42415, Korea.
Children (Basel). 2022 Aug 17;9(8):1241. doi: 10.3390/children9081241.
Headache and allergic rhinitis (AR) are common in children and often co-occur. We investigated the clinical characteristics of pediatric headaches and the association of AR and chronic headaches. We retrospectively reviewed the medical records of patients admitted to our pediatric inpatient and outpatient clinics with complaints of headache between January 2017 and June 2020 for headache-specific history, AR signs and symptoms, allergy skin prick test, inhalant multiple allergen simultaneous test results, laboratory and imaging findings, and medication history. The patients were divided into three subgroups: AR, non-AR, and headache groups, reporting 45.7% patients with headache alone, 13.7% with additional AR, and 31.6% with abnormal imaging findings, suggesting that headache was combined with sinusitis (24.3%) or mastoiditis (7.3%). Furthermore, 6% of the patients had both AR and sinusitis. Body mass index (BMI) differed significantly between the AR and the non-AR and headache groups ( = 0.03). The BMI differed significantly according to headache severity ( ˂ 0.001). The most common allergen was "dust or mites" (41.1%). Acetaminophen (35.9%) was the most commonly used painkiller. The coexistence of AR and headache may indicate that these conditions share a similar pathophysiology. Better management of allergies may facilitate diagnosis, treatment, and prophylaxis of headaches.
头痛和变应性鼻炎(AR)在儿童中很常见,且常同时出现。我们调查了儿童头痛的临床特征以及AR与慢性头痛的关联。我们回顾性分析了2017年1月至2020年6月期间因头痛主诉入住我院儿科门诊和住院部的患者的病历,以获取头痛特异性病史、AR体征和症状、变应原皮肤点刺试验、吸入性多种变应原同时检测结果、实验室和影像学检查结果以及用药史。患者被分为三个亚组:AR组、非AR组和头痛组,结果显示45.7%的患者仅有头痛,13.7%的患者伴有AR,31.6%的患者有异常影像学表现,提示头痛合并鼻窦炎(24.3%)或乳突炎(7.3%)。此外,6%的患者同时患有AR和鼻窦炎。AR组与非AR组及头痛组之间的体重指数(BMI)差异有统计学意义(=0.03)。BMI根据头痛严重程度不同而有显著差异(˂0.001)。最常见的变应原是“灰尘或螨虫”(41.1%)。对乙酰氨基酚(35.9%)是最常用的止痛药。AR和头痛并存可能表明这些病症具有相似的病理生理学机制。更好地管理过敏可能有助于头痛的诊断、治疗和预防。