Dimova Rositsa, Stoyanova Rumyana, Blagoeva Vesela, Mavrov Momchil, Doykov Mladen
Department of Health Management and Health Economics, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.
First Department of Internal Diseases, Section of Pneumology and Phthisiatrics, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.
Healthcare (Basel). 2022 Aug 14;10(8):1535. doi: 10.3390/healthcare10081535.
Until now, the COVID-19 pandemic has resulted in at least 27 million cases and over 900,000 deaths worldwide. Bulgaria is one of the countries that is the most severely affected by the COVID-19 pandemic, and the mortality rate is among the highest registered in the world. The aim of this study is to investigate and analyze mortality rates due to the fact of COVID-19 in addition to the most common related underlying medical conditions in those hospitalized to outline the factors that have an impact on the mortality rate due to the fact of COVID-19. A descriptive cross-sectional research design with a retrospective analysis was used to collect data from a total of 128,269 hospitalized patients during the period from April 2020 to November 2021. During the study period, the number of hospital admissions due to the fact of COVID-19 was 5200. The patients' mean age was 67.34 (SD ± 19.65), and 51.7% (2689) of the patients were men. Only 10% of out of a total of 5200 patients did not test positive for COVID-19 upon admission based on the antigen or PCR test. Out of all patients, 41.5% had no underlying medical conditions upon presentation, and the remaining 58.5% had diagnosed comorbidities, varying from one to five. One-third (1470) had a lethal outcome, and the remaining 71.7% recovered from the infection and were discharged from the hospital. Based on the analysis of our results, there is definite evidence that the CFR and susceptibility to symptomatic COVID-19 were higher in the elderly, men, and patients with more comorbidities, especially chronic cardiovascular, metabolic, and respiratory disorders, as well as in those admitted to hospital within 6 h after an emergency ward visit and who had a shorter mean hospital stay.
截至目前,新冠疫情已在全球导致至少2700万例感染病例和超过90万例死亡。保加利亚是受新冠疫情影响最严重的国家之一,其死亡率位居世界最高之列。本研究的目的是调查和分析新冠疫情导致的死亡率,以及住院患者中最常见的相关基础疾病,以概述影响新冠疫情死亡率的因素。采用描述性横断面研究设计和回顾性分析方法,收集了2020年4月至2021年11月期间共128269例住院患者的数据。在研究期间,因新冠疫情入院的患者有5200例。患者的平均年龄为67.34岁(标准差±19.65),其中51.7%(2689例)为男性。在总共5200例患者中,只有10%在入院时基于抗原或PCR检测未呈新冠病毒阳性。在所有患者中,41.5%在就诊时没有基础疾病,其余58.5%被诊断患有合并症,合并症数量从1种到5种不等。三分之一(1470例)患者死亡,其余71.7%从感染中康复并出院。基于对我们研究结果的分析,有确凿证据表明,老年人、男性以及合并症较多的患者,尤其是患有慢性心血管、代谢和呼吸系统疾病的患者,以及在急诊就诊后6小时内入院且平均住院时间较短的患者,其新冠病毒感染病死率(CFR)和出现症状性新冠感染的易感性更高。