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老年人癌症幸存者的膳食补充剂使用情况:社会人口统计学关联、补充剂类型、使用原因和成本。

Dietary Supplement Use among Older Cancer Survivors: Socio-Demographic Associations, Supplement Types, Reasons for Use, and Cost.

机构信息

Department of Nutrition Sciences, University of Alabama at Birmingham (UAB), Birmingham, AL 35294, USA.

Department of Health Behavior, University of Alabama at Birmingham (UAB), Birmingham, AL 35294, USA.

出版信息

Nutrients. 2022 Aug 18;14(16):3402. doi: 10.3390/nu14163402.

DOI:10.3390/nu14163402
PMID:36014907
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9414522/
Abstract

Most Americans take dietary supplements (DSs) and use is even higher among cancer survivors. This secondary analysis seeks to identify types, reasons, and costs of supplements used by 367 older cancer survivors enrolled in the Harvest for Health vegetable gardening trial and evaluate associations between supplement intake and medical/socio-demographic factors. Descriptive statistics were used to identify supplement type and reasons for use. Average market price was used to estimate cost. Fifty-nine percent of the sample reported supplement use. Female (OR 2.11, 95% CI 1.35-3.30), non-Hispanic White (OR 1.77, 95% CI 1.05-3.0), and breast and gynecological survivors (OR 1.57, 1.03-2.38) were significantly more likely to report DS use compared to males, minorities, and survivors of other cancers. Use of vitamins (39%), multivitamins (23%), and minerals (12%) were the most prevalent. Commonly reported reasons for supplement use were to improve general health (47%) or treat medical conditions (39%) and cancer-related symptoms (12%). DSs daily costs ranged from USD 0.02 to 19.81, with a mean of USD 1.28 ± 1.74, a median of USD 0.78, and a mode of USD 0.34. DS use is prevalent among older cancer survivors, with overall health reported as the leading reason for use. Out-of-pocket recurrent costs can be substantial and underscore the need to promote a nutrient-rich diet whenever possible in this vulnerable population.

摘要

大多数美国人会服用膳食补充剂(DS),癌症幸存者的服用率更高。本二次分析旨在确定参加 Harvest for Health 蔬菜种植试验的 367 名老年癌症幸存者所服用的补充剂类型、原因和费用,并评估补充剂摄入量与医疗/社会人口统计学因素之间的关联。采用描述性统计方法来确定补充剂类型和使用原因。使用平均市场价格来估算成本。样本中有 59%的人报告服用了补充剂。女性(OR 2.11,95%CI 1.35-3.30)、非西班牙裔白人(OR 1.77,95%CI 1.05-3.0)和乳腺癌及妇科癌症幸存者(OR 1.57,95%CI 1.03-2.38)与男性、少数族裔和其他癌症幸存者相比,更有可能报告服用 DS。最常见的补充剂类型包括维生素(39%)、多种维生素(23%)和矿物质(12%)。常见的补充剂使用原因包括改善整体健康(47%)或治疗医疗状况(39%)和癌症相关症状(12%)。DS 每日费用从 0.02 美元到 19.81 美元不等,平均费用为 1.28 美元±1.74 美元,中位数为 0.78 美元,模式为 0.34 美元。老年癌症幸存者中 DS 的使用较为普遍,总体健康是使用的主要原因。自付经常性费用可能很高,这突显了在这个弱势群体中尽可能促进营养丰富的饮食的必要性。

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Dietary Supplement Use among Older Cancer Survivors: Socio-Demographic Associations, Supplement Types, Reasons for Use, and Cost.老年人癌症幸存者的膳食补充剂使用情况:社会人口统计学关联、补充剂类型、使用原因和成本。
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J Nutr. 2020 Jun 1;150(6):1499-1508. doi: 10.1093/jn/nxaa040.
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Dietary supplement use among cancer survivors and the general population: a nation-wide cross-sectional study.癌症幸存者和一般人群中膳食补充剂的使用:一项全国性横断面研究。
BMC Cancer. 2017 Dec 28;17(1):891. doi: 10.1186/s12885-017-3885-1.
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The association between postdiagnosis dietary supplement use and total mortality differs by diet quality among older female cancer survivors.在老年女性癌症幸存者中,诊断后膳食补充剂的使用与总死亡率之间的关联因饮食质量而异。
Cancer Epidemiol Biomarkers Prev. 2014 May;23(5):865-75. doi: 10.1158/1055-9965.EPI-13-1303. Epub 2014 Mar 12.
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Relationships between vitamin and mineral supplement use, dietary intake, and dietary adequacy among adolescents.青少年中维生素和矿物质补充剂的使用、饮食摄入与饮食充足性之间的关系。
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Vitamin and mineral supplement use among US adults after cancer diagnosis: a systematic review.美国成年人癌症诊断后维生素和矿物质补充剂的使用情况:一项系统综述
J Clin Oncol. 2008 Feb 1;26(4):665-73. doi: 10.1200/JCO.2007.13.5905.

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本文引用的文献

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Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement.维生素、矿物质和多种维生素补充剂预防心血管疾病和癌症:美国预防服务工作组推荐声明。
JAMA. 2022 Jun 21;327(23):2326-2333. doi: 10.1001/jama.2022.8970.
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Harvest for Health, a Randomized Controlled Trial Testing a Home-Based, Vegetable Gardening Intervention Among Older Cancer Survivors Across Alabama: An Analysis of Accrual and Modifications Made in Intervention Delivery and Assessment During COVID-19.《健康采摘:一项在阿拉巴马州的老年癌症幸存者中开展的基于家庭的蔬菜种植干预的随机对照试验:对 COVID-19 期间干预措施实施和评估的调整分析》
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Prevalence of Dietary Modification and Supplement Use in Patients with Metastatic Renal Cell Carcinoma Receiving Systemic Therapy.
转移性肾细胞癌患者接受系统治疗时饮食调整和补充剂使用的流行情况。
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Association between dietary supplement use and mortality in cancer survivors with different body mass index and frailty status: a cohort study.不同体重指数和虚弱状态的癌症幸存者使用膳食补充剂与死亡率之间的关联:一项队列研究。
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Dietary supplements could prevent cardiometabolic syndrome: Are they safe and reliable enough for disease prevention and health promotion?膳食补充剂可以预防心脏代谢综合征:它们对于疾病预防和健康促进来说足够安全可靠吗?
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Dietary Supplement Use in Women Diagnosed with Breast Cancer.女性乳腺癌患者的膳食补充剂使用情况。
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