Galanis Petros, Vraka Irene, Siskou Olga, Konstantakopoulou Olympia, Katsiroumpa Aglaia, Kaitelidou Daphne
Clinical Epidemiology Laboratory, Faculty of Nursing, National and Kapodistrian University of Athens, 15773 Athens, Greece.
Department of Radiology, P. & A. Kyriakou Children's Hospital, 15773 Athens, Greece.
Vaccines (Basel). 2022 May 12;10(5):766. doi: 10.3390/vaccines10050766.
Mass vaccination against COVID-19 is essential to control the pandemic. COVID-19 vaccines are now recommended during pregnancy to prevent adverse outcomes. With this review, we aimed to evaluate the evidence in the literature regarding the uptake of COVID-19 vaccinations among pregnant women. A comprehensive search was performed in PubMed, Medline, Scopus, ProQuest, Web of Science, CINAHL, and medRxiv from inception to 23 March 2022. We performed a meta-analysis to estimate the overall proportion of pregnant women vaccinated against COVID-19. We found 11 studies including 703,004 pregnant women. The overall proportion of pregnant women vaccinated against COVID-19 was 27.5% (95% CI: 18.8-37.0%). Predictors of COVID-19 vaccination uptake were older age, ethnicity, race, trust in COVID-19 vaccines, and fear of COVID-19 during pregnancy. Mistrust in the government, diagnosis of COVID-19 during pregnancy, and fears about the safety and side effects of COVID-19 vaccines were reasons for declining vaccination. The global COVID-19 vaccination prevalence in pregnant women is low. A large gap exists in the literature on the factors influencing the decision of pregnant women to be vaccinated against COVID-19. Targeted information campaigns are essential to increase vaccine literacy among pregnant women.
大规模接种新冠疫苗对于控制疫情至关重要。目前建议在孕期接种新冠疫苗以预防不良后果。通过本综述，我们旨在评估文献中关于孕妇接种新冠疫苗情况的证据。从创刊至2022年3月23日，我们在PubMed、Medline、Scopus、ProQuest、Web of Science、CINAHL和medRxiv上进行了全面检索。我们进行了一项荟萃分析，以估计接种新冠疫苗的孕妇的总体比例。我们找到了11项研究，涉及703,004名孕妇。接种新冠疫苗的孕妇总体比例为27.5%（95%置信区间：18.8 - 37.0%）。接种新冠疫苗的预测因素包括年龄较大、种族、民族、对新冠疫苗的信任以及孕期对新冠的恐惧。对政府不信任、孕期确诊感染新冠以及对新冠疫苗安全性和副作用的担忧是拒绝接种疫苗的原因。全球孕妇新冠疫苗接种率较低。关于影响孕妇接种新冠疫苗决策的因素，文献中存在很大差距。有针对性的宣传活动对于提高孕妇的疫苗知识至关重要。
