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基于吲哚菁绿的荧光引导手术在一名患有肛门直肠畸形的男婴中的应用。

Indocyanine Green-Based Fluorescence-Guided Surgery in a Male Infant with Anorectal Malformation.

作者信息

Paraboschi Irene, Privitera Laura, Loukogeorgakis Stavros, Giuliani Stefano

机构信息

Wellcome/EPSRC Centre for Interventional & Surgical Sciences, University College London, London, United Kingdom.

Department of Specialist Neonatal and Pediatric Surgery, Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom.

出版信息

European J Pediatr Surg Rep. 2022 Aug 23;10(1):e122-e125. doi: 10.1055/s-0042-1750029. eCollection 2022 Jan.

Abstract

Reconstructive techniques for complex anorectal malformations (ARMs) require intestinal pull-through on vascular pedicles. Traditionally, the visual inspection of the intestinal perfusion is the sole modality adopted to assess tissue viability. In this article, we report the case of a child with a rectourethral prostatic fistula, who had a Peña's descending colostomy with distal mucous fistula in the neonatal period and a posterior sagittal anorectoplasty at 6 months of life. The ARM repair was guided by indocyanine green (ICG), which was intravenously administered to evaluate the blood flow of the intestinal pull-through using the EleVision IR system (Medtronic Ltd, U.K.). ICG-based fluorescence-guided surgery helped to define the proximal resection margin, impacting intraoperative decision making, and no postoperative complications occurred. We envisage that this technology will become part of the armory of pediatric surgeons soon, by reducing the risk of intra- and postoperative complications.

摘要

复杂肛门直肠畸形(ARM)的重建技术需要在血管蒂上进行肠拖出术。传统上,对肠灌注进行视觉检查是评估组织活力所采用的唯一方式。在本文中,我们报告了一名患有直肠尿道前列腺瘘的儿童病例,该患儿在新生儿期接受了佩尼亚氏降结肠造口术并伴有远端黏液瘘,在6个月大时接受了后矢状位肛门直肠成形术。ARM修复手术由吲哚菁绿(ICG)引导,通过静脉注射ICG,使用EleVision IR系统(英国美敦力有限公司)评估肠拖出术的血流情况。基于ICG的荧光引导手术有助于确定近端切除边缘,影响术中决策,且未发生术后并发症。我们设想,通过降低术中及术后并发症的风险,这项技术很快将成为小儿外科医生的技术储备之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3189/9398569/79947579f0d3/10-1055-s-0042-1750029-i210637cr-1.jpg

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